Difference between revisions of "Oligoastrocytoma"
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# | '''Oligoastrocytoma''' is a rare [[neuropathology tumour]]. | ||
==General== | |||
*Mixed tumour. | |||
==Microscopic== | |||
Features: | |||
*Astrocytoma-like and oligodendroglioma-like: | |||
*#Oligodendroglioma-like cells = round nucleus, peri-nuclear clearing. | |||
*#Astrocytoma-like cells = non-ovoid/elongated nucleus. | |||
DDx: | |||
*Anaplastic astrocytoma. | |||
*Oligodendroglioma. (???) | |||
===IHC=== | |||
*Oligodendroglioma-like cells: MAP-2 +ve (cytoplasm). | |||
*Astrocytoma-like cells: GFAP +ve (cytoplasm, nuclear membrane). | |||
Others: | |||
*Ki-67 ~10%. (???) | |||
*p53 - focally +ve. (???) | |||
*IDH-1 +ve. (85%) | |||
==See also== | |||
*[[Neuropathology tumours]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Neuropathology tumours]] |
Revision as of 06:51, 10 December 2014
Oligoastrocytoma is a rare neuropathology tumour.
General
- Mixed tumour.
Microscopic
Features:
- Astrocytoma-like and oligodendroglioma-like:
- Oligodendroglioma-like cells = round nucleus, peri-nuclear clearing.
- Astrocytoma-like cells = non-ovoid/elongated nucleus.
DDx:
- Anaplastic astrocytoma.
- Oligodendroglioma. (???)
IHC
- Oligodendroglioma-like cells: MAP-2 +ve (cytoplasm).
- Astrocytoma-like cells: GFAP +ve (cytoplasm, nuclear membrane).
Others:
- Ki-67 ~10%. (???)
- p53 - focally +ve. (???)
- IDH-1 +ve. (85%)