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Difference between revisions of "Salivary glands"
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→Pleomorphic adenoma: more details
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(→Pleomorphic adenoma: more details) |
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==Pleomorphic adenoma== | ==Pleomorphic adenoma== | ||
===Epidemiology=== | ===Epidemiology=== | ||
Features:<ref name=Ref_HaNP295>{{Ref HaNP|295}}</ref> | Features: | ||
* | *Very common - approx. 60% of parotid gland tumours.<ref name=Ref_HaNP295>{{Ref HaNP|295}}</ref> | ||
*May transform into a malignant tumour. | |||
**Other benign salivary gland tumours do not do this. | |||
*Only benign childhood salivary gland tumour of significance. | |||
=== | ===Microscopic=== | ||
Features:<ref name=Ref_HaNP295>{{Ref HaNP|295}}</ref> | Features:<ref name=Ref_HaNP295>{{Ref HaNP|295}}</ref> | ||
*Proliferation of myoepithelium and epithelium in mesenchymal stroma. | *Proliferation of myoepithelium and epithelium in mesenchymal stroma. | ||
*Mesenchymal stroma - key feature. | *Mesenchymal stroma - key feature. | ||
**May be any of following: myxoid, mucochondroid, hyalinized, osseous, fatty. | **May be any of following: myxoid, mucochondroid, hyalinized, osseous, fatty. | ||
Notes: | |||
*Complete excision is often elusive; stating "completely excised" on a surgical pathology report is unwise. | |||
*Look for, i.e. rule-out, poorly differentiated carcinoma: ''carcinoma ex pleomorphic adenoma''. | *Look for, i.e. rule-out, poorly differentiated carcinoma: ''carcinoma ex pleomorphic adenoma''. | ||
IHC | ===IHC=== | ||
*S-100 +ve, SMA +ve, GFAP +ve. | |||
==Basal cell adenoma== | ==Basal cell adenoma== | ||