Difference between revisions of "Myofibroma"
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''Myofibroma''' is a soft tissue lesion in the group [[Fibroblastic/myofibroblastic_tumours|fibroblastic/myofibroblastic tumours]]. | '''Myofibroma''' is a soft tissue lesion in the group [[Fibroblastic/myofibroblastic_tumours|fibroblastic/myofibroblastic tumours]]. | ||
==General== | ==General== | ||
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==Gross== | ==Gross== | ||
*Classically (oral) locations: tongue, buccal mucosa, lip.<ref name=pmid20038894/> | *Classically (oral) locations: [[tongue]], buccal mucosa, lip.<ref name=pmid20038894/> | ||
==Microscopic== | ==Microscopic== | ||
Revision as of 22:41, 15 November 2014
Myofibroma is a soft tissue lesion in the group fibroblastic/myofibroblastic tumours.
General
- Benign.
- Often < 2 years old; however, may be seen in adults.
- Not common.[1]
Gross
Microscopic
Features:[1]
- Spindle cells with:
- Tapering nuclei.
- Eosinophilic cytoplasm.
Note:
- Features overlap with myopericytoma.[2]
DDx:
IHC
Features:[1]
- Vimentin +ve.
- SMA +ve.
- S-100 -ve,
See also
References
- ↑ 1.0 1.1 1.2 1.3 Brasileiro, BF.; Martins-Filho, PR.; Piva, MR.; da Silva, LC.; Nonaka, CF.; Miguel, MC. (Jul 2010). "Myofibroma of the oral cavity. A rare spindle cell neoplasm.". Med Oral Patol Oral Cir Bucal 15 (4): e596-600. PMID 20038894. http://www.medicinaoral.com/pubmed/medoralv15_i4_p596.pdf.
- ↑ Dray MS, McCarthy SW, Palmer AA, et al. (January 2006). "Myopericytoma: a unifying term for a spectrum of tumours that show overlapping features with myofibroma. A review of 14 cases". J. Clin. Pathol. 59 (1): 67–73. doi:10.1136/jcp.2005.028704. PMC 1860256. PMID 16394283. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860256/.