Difference between revisions of "Glomangiopericytoma"

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*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311951/figure/Fig1/ SNHPC - low mag. (nih.gov)].<ref name=pmid22430770/>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311951/figure/Fig1/ SNHPC - low mag. (nih.gov)].<ref name=pmid22430770/>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311951/figure/Fig3/ SNHPC - high mag. (nih.gov)].<ref name=pmid22430770>{{Cite journal  | last1 = Brandwein-Gensler | first1 = M. | last2 = Siegal | first2 = GP. | title = Striking pathology gold: a singular experience with daily reverberations: sinonasal hemangiopericytoma (glomangiopericytoma) and oncogenic osteomalacia. | journal = Head Neck Pathol | volume = 6 | issue = 1 | pages = 64-74 | month = Mar | year = 2012 | doi = 10.1007/s12105-012-0337-8 | PMID = 22430770 }}</ref>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311951/figure/Fig3/ SNHPC - high mag. (nih.gov)].<ref name=pmid22430770>{{Cite journal  | last1 = Brandwein-Gensler | first1 = M. | last2 = Siegal | first2 = GP. | title = Striking pathology gold: a singular experience with daily reverberations: sinonasal hemangiopericytoma (glomangiopericytoma) and oncogenic osteomalacia. | journal = Head Neck Pathol | volume = 6 | issue = 1 | pages = 64-74 | month = Mar | year = 2012 | doi = 10.1007/s12105-012-0337-8 | PMID = 22430770 }}</ref>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851559/figure/F3/ SNHPC (nih.gov)].<ref name=pmid24074285/>
==IHC==
Features:<ref name=pmid24074285>{{Cite journal  | last1 = Sun | first1 = Q. | last2 = Zhang | first2 = C. | last3 = Chen | first3 = W. | last4 = He | first4 = Y. | title = The molecular mechanisms on glomangiopericytoma invasion. | journal = Orphanet J Rare Dis | volume = 8 | issue =  | pages = 152 | month =  | year = 2013 | doi = 10.1186/1750-1172-8-152 | PMID = 24074285 }}</ref>
*Vimintin +ve.
*SMA +ve.
*MSA +ve.
*CD31 -ve.
*CD34 -ve.


==See also==
==See also==
Line 29: Line 38:


==References==
==References==
{{Reflist|1}}
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]

Revision as of 01:51, 10 November 2014

Glomangiopericytoma, also known as sinonasal-type hemangiopericytoma and sinonasal hemangiopericytoma,

Sinonasal hemangiopericytoma may be abbreviated SNHPC.[1]

General

  • May be associated with oncogenic osteomalacia.[1]
  • Thought to arise from the pericytes.[2]
  • Rare <1% of sinonasal tumours.[2]

Microscopic

Features:[1]

  • Ahort spindle cells/epithelioid cells with:
    • Bland round/oval nuclei with fine chromatin.
    • Scant cytoplasm.

Note:

  • Superficial submucosal tissue spared.

DDx:

Images

IHC

Features:[3]

  • Vimintin +ve.
  • SMA +ve.
  • MSA +ve.
  • CD31 -ve.
  • CD34 -ve.

See also

References

  1. 1.0 1.1 1.2 1.3 1.4 Brandwein-Gensler, M.; Siegal, GP. (Mar 2012). "Striking pathology gold: a singular experience with daily reverberations: sinonasal hemangiopericytoma (glomangiopericytoma) and oncogenic osteomalacia.". Head Neck Pathol 6 (1): 64-74. doi:10.1007/s12105-012-0337-8. PMID 22430770.
  2. 2.0 2.1 Arpaci, RB.; Kara, T.; Vayisoğlu, Y.; Ozgur, A.; Ozcan, C. (Jul 2012). "Sinonasal glomangiopericytoma.". J Craniofac Surg 23 (4): 1194-6. doi:10.1097/SCS.0b013e31824e6d09. PMID 22801124.
  3. 3.0 3.1 Sun, Q.; Zhang, C.; Chen, W.; He, Y. (2013). "The molecular mechanisms on glomangiopericytoma invasion.". Orphanet J Rare Dis 8: 152. doi:10.1186/1750-1172-8-152. PMID 24074285.