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Difference between revisions of "Metaphyseal fibrous defect"
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Metaphyseal fibrous defect (view source)
Revision as of 06:49, 16 October 2014
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*Often small lesions discovered as an radiographic incidentaloma. | *Often small lesions discovered as an radiographic incidentaloma. | ||
*Rarely seen as a pathologic specimen (should not be biopsied). | *Rarely seen as a pathologic specimen (should not be biopsied). | ||
*May be seen in the context of ''Jaffe-Campanacci syndrome''.<ref>URL: [http://www.bonetumor.org/plasma-cell-tumors/jaffe-campanacci-syndrome http://www.bonetumor.org/plasma-cell-tumors/jaffe-campanacci-syndrome]. Accessed on: October 14, 2014.</ref> | |||
Clinical history: | |||
*Incidental radiographic finding. | |||
*Pathologic fracture. | |||
Prognosis: | |||
*Ideally should not be biopsied. | |||
*Radiographically characteristic and benign. | |||
*Ideally should not be treated or even biopsied. | |||
*Spontaneously resolve by ossification. | |||
*May resolve into a 'bone island'. | |||
==Site== | ==Site== | ||
| Line 50: | Line 62: | ||
==Gross== | ==Gross== | ||
Firm, granular, brown to yellow to red. | *Firm, granular, brown to yellow to red. | ||
==Microscopic== | ==Microscopic== | ||
| Line 71: | Line 83: | ||
==Images== | ==Images== | ||
<gallery> | |||
Image:Bone Metaphyseal Fibrous Defect Medium Power.JPG|Metaphyseal fibrous defect - intermediate magnification.]] | |||
*[http://njms2.umdnj.edu/tutorweb/casegifs/nofhe1.jpg] | Image:Bone Metaphyseal Fibrous Defect High Power.JPG|Metaphyseal fibrous defect - high magnification.]] | ||
*[http://njms2.umdnj.edu/tutorweb/casegifs/nofhe2.jpg] | </gallery> | ||
*[http://njms2.umdnj.edu/tutorweb/casegifs/nofhe1.jpg] | www: | ||
*[http://pathologyoutlines.com/wick/non-ossifying%20fibroma%20(metaphyseal%20fibrous%20defect)%20micro.jpg] | *[http://njms2.umdnj.edu/tutorweb/casegifs/nofhe1.jpg MFD (umdnj.edu)]. | ||
*[http://njms2.umdnj.edu/tutorweb/casegifs/nofhe2.jpg MFD (umdnj.edu)]. | |||
*[http://njms2.umdnj.edu/tutorweb/casegifs/nofhe1.jpg MFD (umdnj.edu)]. | |||
*[http://pathologyoutlines.com/wick/non-ossifying%20fibroma%20(metaphyseal%20fibrous%20defect)%20micro.jpg MFD (pathologyoutlines.com)]. | |||
==Stains== | ==Stains== | ||
Not relevant. | *Not relevant. | ||
==IHC== | ==IHC== | ||
Not relevant | *Not relevant | ||
==Molecular== | ==Molecular== | ||
Not relevant | *Not relevant | ||
==Radiographic findings== | ==Radiographic findings== | ||
| Line 105: | Line 106: | ||
==Sign out== | ==Sign out== | ||
BONE | <pre> | ||
BONE, CURETTAGE: METAPHYSEAL FIBROUS DEFECT / NONOSSIFYING FIBROMA. | |||
</pre> | |||
==See also== | ==See also== | ||
*[[Bone]]. | |||
==References== | |||
{{Reflist|1}} | |||
==External links== | |||
*http://njms2.umdnj.edu/tutorweb/case8.htm | *http://njms2.umdnj.edu/tutorweb/case8.htm | ||
*http://www.pathologyoutlines.com/topic/bonemetaphysealfibrousdefect.html | *http://www.pathologyoutlines.com/topic/bonemetaphysealfibrousdefect.html | ||
*http://radiopaedia.org/articles/fibrous-cortical-defect | *http://radiopaedia.org/articles/fibrous-cortical-defect | ||
*http://radiopaedia.org/articles/non-ossifying-fibroma-1 | *http://radiopaedia.org/articles/non-ossifying-fibroma-1 | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||