Difference between revisions of "Metaphyseal fibrous defect"
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| Width = | | Width = | ||
| Caption = | | Caption = | ||
| Synonyms = | | Synonyms = Nonossifying fibroma | ||
| Micro = spindle cells | | Micro = spindle cells | ||
| Subtypes = | | Subtypes = | ||
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*Skeletally immature individuals, children and adolescent | *Skeletally immature individuals, children and adolescent | ||
*Often small lesions discovered an radiographic incidentaloma | *Often small lesions discovered an radiographic incidentaloma | ||
==Synonyms== | |||
*Nonossifying fibroma | |||
*Fibrous cortical defect | |||
*Fibrous metaphyseal defect | |||
==Site== | |||
*Metaphysis of distal femur or proximal tibia (80%) | |||
*Cortical | |||
*Metaphysis | |||
*Long bones | |||
==Gross== | ==Gross== | ||
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==Molecular== | ==Molecular== | ||
Not relevant | |||
==Syndromes== | |||
Jaffe-Campanacci syndrome | |||
==Clinical history== | |||
*Incidental radiographic finding | |||
*Pathologic fracture | |||
==Radiographic findings== | |||
Sharply demarcated, lucent, loculated, meta-diaphyseal lesion surrounded by a rim of sclerotic bone | |||
==Sign out== | ==Sign out== | ||
BONE; CURETTAGE: METAPHYSEAL FIBROUS DEFECT. | |||
==See also== | ==See also== | ||
Revision as of 07:26, 14 October 2014
| Template:Metaphyseal fibrous defect | |
|---|---|
| Diagnosis in short | |
|
| |
| Synonyms | Nonossifying fibroma |
|
| |
| LM | spindle cells |
| LM DDx | giant cell tumor of bone |
| Syndromes | Jaffe-Campanacci syndrome |
|
| |
| Clinical history | Incidental |
| Radiology | Lucent defect in the metaphysis |
General
- Common
- Non-neoplastic
- Self-limited
- Skeletally immature individuals, children and adolescent
- Often small lesions discovered an radiographic incidentaloma
Synonyms
- Nonossifying fibroma
- Fibrous cortical defect
- Fibrous metaphyseal defect
Site
- Metaphysis of distal femur or proximal tibia (80%)
- Cortical
- Metaphysis
- Long bones
Gross
Firm, granular, brown to yellow to red
Microscopic
Spindle cells without cytologic atypia are arranged in a storiform pattern with scattered chronic inflammatory cells and benign giant cells. Foam cells and hemosiderin deposition are present. Mitoses are seen but cytologic atypia is absent.
Stains
Not relevant.
IHC
Not relevant
Molecular
Not relevant
Syndromes
Jaffe-Campanacci syndrome
Clinical history
- Incidental radiographic finding
- Pathologic fracture
Radiographic findings
Sharply demarcated, lucent, loculated, meta-diaphyseal lesion surrounded by a rim of sclerotic bone
Sign out
BONE; CURETTAGE: METAPHYSEAL FIBROUS DEFECT.
See also
http://njms2.umdnj.edu/tutorweb/case8.htm http://www.pathologyoutlines.com/topic/bonemetaphysealfibrousdefect.html