Difference between revisions of "Pyloric gland adenoma"

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'''Pyloric gland adenoma''' is an uncommon [[gastrointestinal pathology|gastrointestinal]] lesion.
'''Pyloric gland adenoma''', abbreviated '''PGA''', is an uncommon [[gastrointestinal pathology|gastrointestinal]] lesion.


==General==
==General==
*Less than 3% of gastric polyps.<ref>{{Cite journal  | last1 = Vieth | first1 = M. | last2 = Vogel | first2 = C. | last3 = Kushima | first3 = R. | last4 = Borchard | first4 = F. | last5 = Stolte | first5 = M. | title = Pyloric gland adenoma-- how to diagnose? | journal = Cesk Patol | volume = 42 | issue = 1 | pages = 4-7 | month = Jan | year = 2006 | doi =  | PMID = 16506593 }}</ref>
*Less than 3% of gastric polyps.<ref name=pmid16506593>{{Cite journal  | last1 = Vieth | first1 = M. | last2 = Vogel | first2 = C. | last3 = Kushima | first3 = R. | last4 = Borchard | first4 = F. | last5 = Stolte | first5 = M. | title = Pyloric gland adenoma-- how to diagnose? | journal = Cesk Patol | volume = 42 | issue = 1 | pages = 4-7 | month = Jan | year = 2006 | doi =  | PMID = 16506593 }}</ref>
*Associated with [[autoimmune gastritis]].<ref>{{Cite journal  | last1 = Vieth | first1 = M. | last2 = Montgomery | first2 = EA. | title = Some observations on pyloric gland adenoma: an uncommon and long ignored entity! | journal = J Clin Pathol | volume =  | issue =  | pages =  | month = Aug | year = 2014 | doi = 10.1136/jclinpath-2014-202553 | PMID = 25092673 }}</ref>
*Associated with [[autoimmune gastritis]].<ref>{{Cite journal  | last1 = Vieth | first1 = M. | last2 = Montgomery | first2 = EA. | title = Some observations on pyloric gland adenoma: an uncommon and long ignored entity! | journal = J Clin Pathol | volume =  | issue =  | pages =  | month = Aug | year = 2014 | doi = 10.1136/jclinpath-2014-202553 | PMID = 25092673 }}</ref>



Revision as of 04:56, 6 September 2014

Pyloric gland adenoma, abbreviated PGA, is an uncommon gastrointestinal lesion.

General

Microscopic

DDx:

IHC

  • Ki-67 high.
  • MUC6 +ve.[3]
    • Negative in foveolar-type gastric adenomas.
  • MUC5AC +ve.[3]

References

  1. Vieth, M.; Vogel, C.; Kushima, R.; Borchard, F.; Stolte, M. (Jan 2006). "Pyloric gland adenoma-- how to diagnose?". Cesk Patol 42 (1): 4-7. PMID 16506593.
  2. Vieth, M.; Montgomery, EA. (Aug 2014). "Some observations on pyloric gland adenoma: an uncommon and long ignored entity!". J Clin Pathol. doi:10.1136/jclinpath-2014-202553. PMID 25092673.
  3. 3.0 3.1 Chen, ZM.; Scudiere, JR.; Abraham, SC.; Montgomery, E. (Feb 2009). "Pyloric gland adenoma: an entity distinct from gastric foveolar type adenoma.". Am J Surg Pathol 33 (2): 186-93. doi:10.1097/PAS.0b013e31817d7ff4. PMID 18830123.