Difference between revisions of "Ganglion cyst"
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| Gross = | | Gross = | ||
| Grossing = | | Grossing = | ||
| Site = [[soft tissue lesions|soft tissue]] - esp. hand | | Site = [[soft tissue lesions|soft tissue]] close to [[joints]] - esp. in hand | ||
| Assdx = | | Assdx = | ||
| Syndromes = | | Syndromes = | ||
Revision as of 06:14, 17 August 2014
| Ganglion cyst | |
|---|---|
| Diagnosis in short | |
 Ganglion cyst of the hand. H&E stain. | |
|
| |
| LM | empty space(s) - usually multiple; fibrotic wall without an epithelial lining +/- myxoid change +/- spindled fibroblasts |
| LM DDx | synovial cyst, juxta-articular myxoma, (other) myxomas, digital mucous cyst |
| Site | soft tissue close to joints - esp. in hand |
|
| |
| Prevalence | common |
| Prognosis | benign |
Ganglion cyst is a small benign ditzel classically found on the wrist.
General
Gross
- Mass at a joint - classically in the hand.
DDx - clinical:
- Metacarpal boss - degenerative arthritis.[4]
- Giant cell tumour of tendon sheath.
Microscopic
- Empty space(s); usually multiple.
- Fibrotic wall.
- No epithelial lining.†
- +/-Myxoid change - very common.
- May have some spindled fibroblasts.
† The entity is really a pseudocyst.[1]
DDx:
- Synovial cyst - true cyst (has an epithelial lining), villous projections into the cystic space.
- Juxta-articular myxoma.
- Myxoma.
- Digital mucous cyst - has many spindled fibroblasts, usu. superficial.[3]
Images
Ganglion cyst of the hand. (WC/Uthman)
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SOFT TISSUE ("GANGLION CYST"), LEFT WRIST, EXCISION:
- GANGLION CYST.
Micro
The sections show fibroadipose tissue with cyst-like spaces surrounded by fibrous tissue. There are no villous projections into the cyst-like spaces. Focal myxoid areas are present with rare bland spindle cells. There is no nuclear atypia and no mitotic activity is appreciated. Dense connective tissue consistent with tendon is present focally.
Alternate
The sections show cyst-like spaces surrounded by fibrous tissue. There are no villous projections into the cyst-like spaces. Focal myxoid areas are present with rare bland spindle cells. There is no nuclear atypia and no mitotic activity is appreciated. Dense connective tissue consistent with tendon is present focally. Benign glands are present.
See also
References
- ↑ 1.0 1.1 1.2 URL: http://emedicine.medscape.com/article/1253223-overview]. Accessed on: 8 February 2012. Cite error: Invalid
<ref>tag; name "emed_gc" defined multiple times with different content - ↑ Hasham, S.; Burke, FD. (May 2007). "Diagnosis and treatment of swellings in the hand.". Postgrad Med J 83 (979): 296-300. doi:10.1136/pgmj.2005.043992. PMID 17488856.
- ↑ 3.0 3.1 3.2 Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 322. ISBN 978-0443066542.
- ↑ Cuono, CB.; Watson, HK. (Jan 1979). "The carpal boss: surgical treatment and etiological considerations.". Plast Reconstr Surg 63 (1): 88-93. PMID 432327.