Difference between revisions of "Chorioamnionitis"

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| Grossing  =
| Grossing  =
| Site      = [[placenta]]
| Site      = [[placenta]]
| Assdx      = [[umbilical cord vasculitis]], [[funisitis]]
| Assdx      = [[umbilical cord vasculitis]], [[funisitis]], [[placental meconium]]
| Syndromes  =
| Syndromes  =
| Clinicalhx = +/-premature rupture of membranes, +/-preterm labour, +/-failure to progress
| Clinicalhx = +/-premature rupture of membranes, +/-preterm labour, +/-failure to progress
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| Prognosis  = good
| Prognosis  = good
| Other      =
| Other      =
| ClinDDx    =
| ClinDDx    = other causes of maternal fever and fetal tachycardia
| Tx        = antibiotics
}}
}}
'''Chorioamnionitis''' is a common pathology of the [[placenta]].
'''Chorioamnionitis''' is a common pathology of the [[placenta]].
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*Neutrophils in the amnion.
*Neutrophils in the amnion.
**Amnion:  
**Amnion:  
***The simple cuboidal epithelium and the paucicellular underlying connective tissue
***The simple cuboidal epithelium and the paucicellular underlying connective tissue.
***Separated from the chorion by an artefactual cleft.
***Separated from the chorion by an artefactual cleft.
*+/-Microorganisms (e.g. cocci<ref>{{Cite journal  | last1 = Murdoch | first1 = DA. | title = Gram-positive anaerobic cocci. | journal = Clin Microbiol Rev | volume = 11 | issue = 1 | pages = 81-120 | month = Jan | year = 1998 | doi =  | PMID = 9457430 | PMC = 121377}}
*+/-Microorganisms (e.g. cocci<ref>{{Cite journal  | last1 = Murdoch | first1 = DA. | title = Gram-positive anaerobic cocci. | journal = Clin Microbiol Rev | volume = 11 | issue = 1 | pages = 81-120 | month = Jan | year = 1998 | doi =  | PMID = 9457430 | PMC = 121377}}
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Note:
Note:
*Severe cases may have [[umbilical cord vasculitis]] or [[funisitis]].
*Severe cases may have [[umbilical cord vasculitis]] or [[funisitis]].
DDx:
*[[Membranitis]].
*[[Placental meconium]] - associated with degeneration (apoptotic cells).
*Intramembrane bleed - rare [[neutrophil]]s with [[red blood cell]]s in the amnion without significant neutrophils in the chorion and decidua.


===Images===
===Images===
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</pre>
</pre>


===Chorioamnionitis and funisitis===
===Chorioamnionitis with vasculitis===
<pre>
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION:
- CHORIOAMNIONITIS, MODERATE.
- THREE VESSEL UMBILICAL CORD WITH VASCULITIS, EARLY.
- FETAL MEMBRANES NEGATIVE FOR MECONIUM.
- PLACENTAL DISC WITH THIRD TRIMESTER VILLI.
</pre>
 
===Chorioamnionitis with funisitis===
<pre>
<pre>
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION:
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION:
49,294

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