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Difference between revisions of "Chorioamnionitis"
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| Width = | | Width = | ||
| Caption = Chorioamnionitis. [[H&E stain]]. | | Caption = Chorioamnionitis. [[H&E stain]]. | ||
| Micro = | | Micro = [[neutrophil]]s present in the amnion, usu. associated with abundant subchorionic neutrophils | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = [[membranitis]] | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = | ||
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| Molecular = | | Molecular = | ||
| IF = | | IF = | ||
| Gross = | | Gross = +/-opaque membranes | ||
| Grossing = | | Grossing = | ||
| Site = [[placenta]] | | Site = [[placenta]] | ||
| Assdx = [[funisitis]] | | Assdx = [[umbilical cord vasculitis]], [[funisitis]], [[placental meconium]] | ||
| Syndromes = | | Syndromes = | ||
| Clinicalhx = | | Clinicalhx = +/-premature rupture of membranes, +/-preterm labour, +/-failure to progress | ||
| Signs = fetal tachycardia, maternal fever | | Signs = fetal tachycardia, maternal fever, nonreassuring fetal heart rate | ||
| Symptoms = | | Symptoms = | ||
| Prevalence = common | | Prevalence = common | ||
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| Prognosis = good | | Prognosis = good | ||
| Other = | | Other = | ||
| ClinDDx = | | ClinDDx = other causes of maternal fever and fetal tachycardia | ||
| Tx = antibiotics | |||
}} | }} | ||
'''Chorioamnionitis''' is a common pathology of the [[placenta]]. | '''Chorioamnionitis''' is a common pathology of the [[placenta]]. | ||
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*Neutrophils in the amnion. | *Neutrophils in the amnion. | ||
**Amnion: | **Amnion: | ||
***The simple cuboidal epithelium and the paucicellular underlying connective tissue | ***The simple cuboidal epithelium and the paucicellular underlying connective tissue. | ||
***Separated from the chorion by an artefactual cleft. | ***Separated from the chorion by an artefactual cleft. | ||
*+/-Microorganisms (e.g. cocci<ref>{{Cite journal | last1 = Murdoch | first1 = DA. | title = Gram-positive anaerobic cocci. | journal = Clin Microbiol Rev | volume = 11 | issue = 1 | pages = 81-120 | month = Jan | year = 1998 | doi = | PMID = 9457430 | PMC = 121377}} | *+/-Microorganisms (e.g. cocci<ref>{{Cite journal | last1 = Murdoch | first1 = DA. | title = Gram-positive anaerobic cocci. | journal = Clin Microbiol Rev | volume = 11 | issue = 1 | pages = 81-120 | month = Jan | year = 1998 | doi = | PMID = 9457430 | PMC = 121377}} | ||
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Note: | Note: | ||
*Severe cases may have umbilical cord vasculitis or [[funisitis]]. | *Severe cases may have [[umbilical cord vasculitis]] or [[funisitis]]. | ||
DDx: | |||
*[[Membranitis]]. | |||
*[[Placental meconium]] - associated with degeneration (apoptotic cells). | |||
*Intramembrane bleed - rare [[neutrophil]]s with [[red blood cell]]s in the amnion without significant neutrophils in the chorion and decidua. | |||
===Images=== | ===Images=== | ||
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</pre> | </pre> | ||
===Chorioamnionitis | ===Chorioamnionitis with vasculitis=== | ||
<pre> | |||
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION: | |||
- CHORIOAMNIONITIS, MODERATE. | |||
- THREE VESSEL UMBILICAL CORD WITH VASCULITIS, EARLY. | |||
- FETAL MEMBRANES NEGATIVE FOR MECONIUM. | |||
- PLACENTAL DISC WITH THIRD TRIMESTER VILLI. | |||
</pre> | |||
===Chorioamnionitis with funisitis=== | |||
<pre> | <pre> | ||
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION: | PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION: | ||