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(→Neuroma: new section) |
m (→Hemangioblastoma: modify) |
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The sections show a partially cystic vascular tumour with histomorphological normal endothelial cells and vacuolated polygonal cells with hyperchromatic nuclei. There is no mitotic activity. The tumour has a poorly demarcated border. Cerebellum adjacent to the tumour demonstrates Purkinje cell loss and Bergmann gliosis. | The sections show a partially cystic vascular tumour with histomorphological normal endothelial cells and vacuolated polygonal cells with hyperchromatic nuclei. There is no mitotic activity. The tumour has a poorly demarcated border. Cerebellum adjacent to the tumour demonstrates Purkinje cell loss and Bergmann gliosis. | ||
The large polygonal cells have cytoplasmic staining with alpha-inhibin and neuron-specific enolase (NSE). The tumour does not stain for EMA. | |||
===Final diagnosis=== | ===Final diagnosis=== | ||
BRAIN, CEREBELLUM, EXCISION: | BRAIN, CEREBELLUM, EXCISION: | ||
<br> - HEMANGIOBLASTOMA. | <br> - HEMANGIOBLASTOMA. | ||
==Metastatic large cell carcinoma== | ==Metastatic large cell carcinoma== |
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