Difference between revisions of "Papillary urothelial neoplasm of low malignant potential"

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      =
| Width      =
| Caption    =
| Synonyms  =
| Micro      = rare fused papillae, infrequent mitoses, nuclei larger than papilloma - but monotonous
| Subtypes  =
| LMDDx      = [[low grade papillary urothelial carcinoma]], [[urothelial papilloma]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[urothelium]]
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = uncommon
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  =
| Other      =
| ClinDDx    =
| Tx        = excision and on-going follow-up - like non-invasive [[low grade papillary urothelial carcinoma]]
}}
'''Papillary urothelial neoplasm of low malignant potential''', abbreviated '''PUNLMP''', is an uncommon [[urothelium|urothelial]] lesion that is similar to [[low-grade papillary urothelial carcinoma]].
'''Papillary urothelial neoplasm of low malignant potential''', abbreviated '''PUNLMP''', is an uncommon [[urothelium|urothelial]] lesion that is similar to [[low-grade papillary urothelial carcinoma]].


Revision as of 23:28, 30 April 2014

Papillary urothelial neoplasm of low malignant potential
Diagnosis in short
LM rare fused papillae, infrequent mitoses, nuclei larger than papilloma - but monotonous
LM DDx low grade papillary urothelial carcinoma, urothelial papilloma
Site urothelium
Prevalence uncommon
Treatment excision and on-going follow-up - like non-invasive low grade papillary urothelial carcinoma

Papillary urothelial neoplasm of low malignant potential, abbreviated PUNLMP, is an uncommon urothelial lesion that is similar to low-grade papillary urothelial carcinoma.

PUNLMP is pronounced pun-lump.

General

Treatment:

Microscopic

Features:[5]

  • Rare fused papillae.
  • Infrequent mitoses.
  • Nuclei larger than papilloma - but monotonous.[6]

DDx:

Images

  • PUNLMP - low mag. (WC/Nephron)

  • PUNLMP - high mag. (WC/Nephron)

See also

References

  1. ↑ May M, Brookman-Amissah S, Roigas J, et al. (March 2009). "Prognostic Accuracy of Individual Uropathologists in Noninvasive Urinary Bladder Carcinoma: A Multicentre Study Comparing the 1973 and 2004 World Health Organisation Classifications". Eur. Urol. 57 (5): 850. doi:10.1016/j.eururo.2009.03.052. PMID 19346063.
  2. ↑ MacLennan GT, Kirkali Z, Cheng L (April 2007). "Histologic grading of noninvasive papillary urothelial neoplasms". Eur. Urol. 51 (4): 889–97; discussion 897–8. doi:10.1016/j.eururo.2006.10.037. PMID 17095142.
  3. ↑ Jones TD, Cheng L (June 2006). "Papillary urothelial neoplasm of low malignant potential: evolving terminology and concepts". J. Urol. 175 (6): 1995–2003. doi:10.1016/S0022-5347(06)00267-9. PMID 16697785.
  4. ↑ Cheng, L.; Maclennan, GT.; Lopez-Beltran, A. (Dec 2012). "Histologic grading of urothelial carcinoma: a reappraisal.". Hum Pathol 43 (12): 2097-108. doi:10.1016/j.humpath.2012.01.008. PMID 22542126.
  5. ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 310. ISBN 978-0781765275.
  6. ↑ Zhou, Ming; Magi-Galluzzi, Cristina (2006). Genitourinary Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 170. ISBN 978-0443066771.
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