Difference between revisions of "Intradermal nevus"

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#redirect [[Melanocytic lesions#Intradermal melanocytic nevus]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Intradermal nevus -- intermed mag.jpg
| Width      =
| Caption    = Intradermal nevus. [[H&E stain]].
| Synonyms  = intradermal melanocytic nevus
| Micro      = nests of melanocytes in dermis (only), melanocytes "mature" with depth, usu. no mitoses (occ. superficial), no destruction of surrounding structures, no conspicuous nucleoli, no significant melanocyte enlargement
| Subtypes  =
| LMDDx      = [[malignant melanoma]] (nevoid), [[junctional nevus]], [[compound nevus]], [[dysplastic nevus]], [[skin tag]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      = pigment skin lesion, usu. small, regular border, no irregularity in pigmentation
| Grossing  =
| Site      = [[skin]] - see ''[[melanocytic lesions]]'' and ''[[common nevus]]''
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = very common
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    = pigmented skin lesions
| Tx        = none required, may be excised for cosmetic reasons
}}
'''Intradermal nevus''' (abbreviated '''IDN'''), also '''intradermal melanocytic nevus''', is a common benign [[melanocytic lesion]].
 
The ''intradermal nevus'' is in the large group '''[[common nevus]]'''. In common language, ''nevus'' is known as a ''mole''.
 
==General==
*Benign.
*Common.
*Think ''[[melanoma]]''.
 
Clinical:
*''ABCD'' = asymmetric, borders (irregular), colour (black), diameter (large).
 
==Microscopic==
Features:
*Symmetrical lesion.
*"Matures" with depth.
**Less cellular with depth.
**Less nuclear atypia with depth.
**Smaller cells with depth.
**Smaller nests with depth.
*Rare mitoses (superficial).
**No deep mitoses.
*No destruction of surrounding structures.
*No nucleoli.
*In the dermis only - '''key feature'''.
*+/-Adipocytes - uncommon.<ref name=pmid9810886>{{Cite journal  | last1 = Eng | first1 = W. | last2 = Cohen | first2 = PR. | title = Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells. | journal = J Am Acad Dermatol | volume = 39 | issue = 5 Pt 1 | pages = 704-11 | month = Nov | year = 1998 | doi =  | PMID = 9810886 }}</ref>
 
DDx:
*[[Malignant melanoma]] (nevoid).
*[[Dysplastic nevus]].
*[[Junctional nevus]].
*[[Compound nevus]].
*[[Skin tag]].
 
===Images===
<gallery>
Image: Intradermal nevus -- very low mag.jpg | IDN - very low mag.
Image: Intradermal nevus -- low mag.jpg | IDN - low mag.
Image: Intradermal nevus -- intermed mag.jpg | IDN - intermed. mag.
Image: Intradermal nevus -- high mag.jpg | IDN - high mag.
Image: Intradermal nevus -- very high mag.jpg | IDN - very high mag.
</gallery>
 
==Sign out==
 
 
==See also==
*[[Melanocytic lesions]].
 
==References==
{{Reflist|2}}
 
[[Category:Diagnosis]]
[[Category:Melanocytic lesions]]

Revision as of 00:08, 20 April 2014

Intradermal nevus
Diagnosis in short

Intradermal nevus. H&E stain.
Synonyms intradermal melanocytic nevus
LM nests of melanocytes in dermis (only), melanocytes "mature" with depth, usu. no mitoses (occ. superficial), no destruction of surrounding structures, no conspicuous nucleoli, no significant melanocyte enlargement
LM DDx malignant melanoma (nevoid), junctional nevus, compound nevus, dysplastic nevus, skin tag
Gross pigment skin lesion, usu. small, regular border, no irregularity in pigmentation
Site skin - see melanocytic lesions and common nevus
Prevalence very common
Prognosis benign
Clin. DDx pigmented skin lesions
Treatment none required, may be excised for cosmetic reasons

Intradermal nevus (abbreviated IDN), also intradermal melanocytic nevus, is a common benign melanocytic lesion.

The intradermal nevus is in the large group common nevus. In common language, nevus is known as a mole.

General

Clinical:

  • ABCD = asymmetric, borders (irregular), colour (black), diameter (large).

Microscopic

Features:

  • Symmetrical lesion.
  • "Matures" with depth.
    • Less cellular with depth.
    • Less nuclear atypia with depth.
    • Smaller cells with depth.
    • Smaller nests with depth.
  • Rare mitoses (superficial).
    • No deep mitoses.
  • No destruction of surrounding structures.
  • No nucleoli.
  • In the dermis only - key feature.
  • +/-Adipocytes - uncommon.[1]

DDx:

Images

  • IDN - very low mag.

  • IDN - low mag.

  • IDN - intermed. mag.

  • IDN - high mag.

  • IDN - very high mag.

Sign out

See also

References

  1. ↑ Eng, W.; Cohen, PR. (Nov 1998). "Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells.". J Am Acad Dermatol 39 (5 Pt 1): 704-11. PMID 9810886.
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