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Difference between revisions of "Thymus"
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→Thymic carcinoma
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Features:<ref name=Ref_WMSP147>{{Ref WMSP|147}}</ref> | Features:<ref name=Ref_WMSP147>{{Ref WMSP|147}}</ref> | ||
*Cytologically malignant - variable morphology. | *Cytologically malignant - variable morphology. | ||
**[[Squamous cell carcinoma]] is the most common (73% of cases | **[[Squamous cell carcinoma]] is the most common (65-73% of cases<ref name=pmid23319214>{{Cite journal | last1 = Thomas de Montpréville | first1 = V. | last2 = Ghigna | first2 = MR. | last3 = Lacroix | first3 = L. | last4 = Besse | first4 = B. | last5 = Broet | first5 = P. | last6 = Dartevelle | first6 = P. | last7 = Fadel | first7 = E. | last8 = Dorfmuller | first8 = P. | title = Thymic carcinomas: clinicopathologic study of 37 cases from a single institution. | journal = Virchows Arch | volume = 462 | issue = 3 | pages = 307-13 | month = Mar | year = 2013 | doi = 10.1007/s00428-013-1371-y | PMID = 23319214 }}</ref><ref name=pmid23866799>{{Cite journal | last1 = Zhao | first1 = Y. | last2 = Zhao | first2 = H. | last3 = Hu | first3 = D. | last4 = Fan | first4 = L. | last5 = Shi | first5 = J. | last6 = Fang | first6 = W. | title = Surgical treatment and prognosis of thymic squamous cell carcinoma: a retrospective analysis of 105 cases. | journal = Ann Thorac Surg | volume = 96 | issue = 3 | pages = 1019-24 | month = Sep | year = 2013 | doi = 10.1016/j.athoracsur.2013.04.078 | PMID = 23866799 }}</ref>). | ||
*+/-Squamous differentiation. | *+/-Squamous differentiation. | ||
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===IHC=== | ===IHC=== | ||
Features:<ref name=Ref_WMSP147>{{Ref WMSP|147}}</ref> | Features:<ref name=Ref_WMSP147>{{Ref WMSP|147}}</ref> | ||
*CD5 +ve.<ref name=Ref_PBoD708>{{Ref PBoD|708}}</ref> | *CD5 +ve (90% of cases<ref name=pmid23319214/>).<ref name=Ref_PBoD708>{{Ref PBoD|708}}</ref> | ||
* | *CD117 +ve (87% of cases<ref name=pmid23319214/>). | ||
* | *CD7 +ve. | ||
*TTF-1 -ve. | *TTF-1 -ve. | ||