Difference between revisions of "Esophageal stricture"
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'''Esophageal stricture''' is a [[clinical diagnosis]]. Considered broadly, strictures may be benign or [[malignant]]. | '''Esophageal stricture''' is usually a [[clinical diagnosis]]. Considered broadly, strictures may be benign or [[malignant]]. | ||
This article deals with benign | This article deals primarily with '''benign stricture of the [[esophagus]]''' or '''benign esophageal stricture'''. | ||
==General== | ==General== | ||
Strictures in general: | |||
*Malignant - it is the pathologist's job to help rule-out these. | |||
*Benign. | |||
*Most are distal.<ref name=pmid6512226>{{Cite journal | last1 = Kozarek | first1 = RA. | title = Proximal strictures of the esophagus. | journal = J Clin Gastroenterol | volume = 6 | issue = 6 | pages = 505-11 | month = Dec | year = 1984 | doi = | PMID = 6512226 }}</ref> | |||
Treatment: | Treatment: | ||
*Stenting.<ref name=pmid24117639>{{Cite journal | last1 = Hourneaux de Moura | first1 = EG. | last2 = Toma | first2 = K. | last3 = Goh | first3 = KL. | last4 = Romero | first4 = R. | last5 = Dua | first5 = KS. | last6 = Felix | first6 = VN. | last7 = Levine | first7 = MS. | last8 = Kochhar | first8 = R. | last9 = Appasani | first9 = S. | title = Stents for benign and malignant esophageal strictures. | journal = Ann N Y Acad Sci | volume = 1300 | issue = | pages = 119-43 | month = Oct | year = 2013 | doi = 10.1111/nyas.12242 | PMID = 24117639 }}</ref> | *Stenting.<ref name=pmid24117639>{{Cite journal | last1 = Hourneaux de Moura | first1 = EG. | last2 = Toma | first2 = K. | last3 = Goh | first3 = KL. | last4 = Romero | first4 = R. | last5 = Dua | first5 = KS. | last6 = Felix | first6 = VN. | last7 = Levine | first7 = MS. | last8 = Kochhar | first8 = R. | last9 = Appasani | first9 = S. | title = Stents for benign and malignant esophageal strictures. | journal = Ann N Y Acad Sci | volume = 1300 | issue = | pages = 119-43 | month = Oct | year = 2013 | doi = 10.1111/nyas.12242 | PMID = 24117639 }}</ref> | ||
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==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Squamous mucosa: | *Squamous mucosa with irritation: | ||
**+/-Keratinization. | **+/-Keratinization. | ||
**Intraepithelial lymphocytes. | **Intraepithelial lymphocytes. | ||
**Basal cell hyperplasia. | **Basal cell hyperplasia. | ||
*Fibrosis (deep) - usually not seen. | |||
DDx: | DDx: | ||
*[[GERD]]. | *[[GERD]]. | ||
*[[Barrett's esophagus]]. | |||
*[[Squamous cell carcinoma of the esophagus]]. | *[[Squamous cell carcinoma of the esophagus]]. | ||
*[[Adenocarcinoma of the esophagus]]. | *[[Adenocarcinoma of the esophagus]]. | ||
| Line 33: | Line 40: | ||
==See also== | ==See also== | ||
*[[Esophagus]]. | *[[Esophagus]]. | ||
*[[Achalasia]]. | |||
==References== | ==References== | ||
Latest revision as of 02:59, 22 February 2014
Esophageal stricture is usually a clinical diagnosis. Considered broadly, strictures may be benign or malignant.
This article deals primarily with benign stricture of the esophagus or benign esophageal stricture.
General
Strictures in general:
- Malignant - it is the pathologist's job to help rule-out these.
- Benign.
- Most are distal.[1]
Treatment:
Microscopic
Features:
- Squamous mucosa with irritation:
- +/-Keratinization.
- Intraepithelial lymphocytes.
- Basal cell hyperplasia.
- Fibrosis (deep) - usually not seen.
DDx:
- GERD.
- Barrett's esophagus.
- Squamous cell carcinoma of the esophagus.
- Adenocarcinoma of the esophagus.
Sign out
ESOPHAGUS, BIOPSY: - SQUAMOUS MUCOSA WITH BASAL CELL HYPERPLASIA, MILD INTRAEPITHELIAL EDEMA, FOCAL EARLY KERATINIZATION AND INTRAEPITHELIAL LYMPHOCYTES. - SCANT COLUMNAR EPITHELIUM WITH MODERATE CHRONIC INACTIVE INFLAMMATION. - NEGATIVE FOR INTESTINAL METAPLASIA. - NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY.
See also
References
- ↑ Kozarek, RA. (Dec 1984). "Proximal strictures of the esophagus.". J Clin Gastroenterol 6 (6): 505-11. PMID 6512226.
- ↑ Hourneaux de Moura, EG.; Toma, K.; Goh, KL.; Romero, R.; Dua, KS.; Felix, VN.; Levine, MS.; Kochhar, R. et al. (Oct 2013). "Stents for benign and malignant esophageal strictures.". Ann N Y Acad Sci 1300: 119-43. doi:10.1111/nyas.12242. PMID 24117639.
- ↑ Singhal, S.; Hasan, SS.; Cohen, DC.; Pfanner, T.; Reznik, S.; Duddempudi, S. (Sep 2013). "Multi-disciplinary approach for management of refractory benign occlusive esophageal strictures.". Therap Adv Gastroenterol 6 (5): 365-70. doi:10.1177/1756283X13492000. PMID 24003337.