Difference between revisions of "Subependymoma"
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| Clinicalhx = | | Clinicalhx = | ||
| Signs = | | Signs = | ||
| Symptoms = | | Symptoms = +/-headache | ||
| Prevalence = | | Prevalence = | ||
| Bloodwork = | | Bloodwork = | ||
| Line 28: | Line 28: | ||
| Other = | | Other = | ||
| ClinDDx = other brain tumours - [[ependymoma]], [[CNS lymphoma]] | | ClinDDx = other brain tumours - [[ependymoma]], [[CNS lymphoma]] | ||
| Tx = | | Tx = surgical excision | ||
}} | }} | ||
'''Subependymoma''' is [[neuropathology]] tumour classically found in the fourth ventricle. | '''Subependymoma''' is [[neuropathology]] tumour classically found in the fourth ventricle. | ||
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==General== | ==General== | ||
*Good prognosis - WHO Grade I. | *Good prognosis - WHO Grade I. | ||
*Low-grade glial tumour.<ref name=pmid23483468/> | |||
Clinical:<ref name=pmid23483468>{{Cite journal | last1 = Castro-Castro | first1 = J. | last2 = Castro-Bouzas | first2 = D. | last3 = Prieto-Casal | first3 = PL. | last4 = Carcacia-Hermilla | first4 = ID. | last5 = Riu-Lloveras | first5 = M. | last6 = Castro-Gómez | first6 = JE. | title = [Subependymoma of the lateral ventricle. A case report]. | journal = Rev Neurol | volume = 56 | issue = 6 | pages = 332-6 | month = Mar | year = 2013 | doi = | PMID = 23483468 }} | |||
</ref> | |||
*Slow growing. | |||
*+/-Headaches. | |||
*Tx: surgery. | |||
==Gross/radiology== | ==Gross/radiology== | ||
| Line 48: | Line 55: | ||
Negatives. | Negatives. | ||
*No nuclear pleomorphism, no prominent nucleoli, no mitoses. | *No nuclear pleomorphism, no prominent nucleoli, no mitoses. | ||
*Do not invade into brain.<ref name=pmid23483468/> | |||
===Images=== | ===Images=== | ||
Revision as of 03:03, 17 February 2014
| Subependymoma | |
|---|---|
| Diagnosis in short | |
 Subependymoma. H&E stain. | |
|
| |
| LM | microcysts with bluish material (give a spongy appearance at low magnification), clustering of nuclei cluster (described as "bundles of flowers"), bland nuclei |
| Site | brain - see neuropathology tumours |
|
| |
| Symptoms | +/-headache |
| Radiology | classically fourth ventricle |
| Prognosis | WHO grade I |
| Clin. DDx | other brain tumours - ependymoma, CNS lymphoma |
| Treatment | surgical excision |
Subependymoma is neuropathology tumour classically found in the fourth ventricle.
General
- Good prognosis - WHO Grade I.
- Low-grade glial tumour.[1]
Clinical:[1]
- Slow growing.
- +/-Headaches.
- Tx: surgery.
Gross/radiology
- Classic location: fourth ventricle.[2]
- Well-demarcated margin.
- Usu. completely within the ventricle; does not extend into brain (like ependymomas).
Microscopic
Features:[3]
- Microcysts with bluish material - give a spongy appearance at low magnification.
- Nuclei cluster.
- Described as "bundles of flowers".
Negatives.
- No nuclear pleomorphism, no prominent nucleoli, no mitoses.
- Do not invade into brain.[1]
Images
www:
Subependyoma - intermed. mag. (WC)
Subependymoma - high mag. (WC)
Subependymoma - very high mag. (WC)
See also
References
- ↑ 1.0 1.1 1.2 Castro-Castro, J.; Castro-Bouzas, D.; Prieto-Casal, PL.; Carcacia-Hermilla, ID.; Riu-Lloveras, M.; Castro-Gómez, JE. (Mar 2013). "[Subependymoma of the lateral ventricle. A case report].". Rev Neurol 56 (6): 332-6. PMID 23483468.
- ↑ Hoeffel, C.; Boukobza, M.; Polivka, M.; Lot, G.; Guichard, JP.; Lafitte, F.; Reizine, D.; Merland, JJ.. "MR manifestations of subependymomas.". AJNR Am J Neuroradiol 16 (10): 2121-9. PMID 8585504. http://www.ajnr.org/cgi/reprint/16/10/2121.
- ↑ 3.0 3.1 URL: http://moon.ouhsc.edu/kfung/jty1/Com05/Com501-2-Diss.htm. Accessed on: 2 June 2011.