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Nevus lipomatosus superficialis (view source)
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'''Nevus lipomatosus superficialis''', abbreviated '''NLS''', is an uncommon benign skin lesion seen on young adults. | |||
It is also known as '''nevus lipomatosus cutaneous superficialis''' (abbreviated '''NLCS''') and '''nevus lipomatosus'''.<ref name=pmid15677959>{{Cite journal | last1 = Kaw | first1 = P. | last2 = Carlson | first2 = A. | last3 = Meyer | first3 = DR. | title = Nevus lipomatosus (pedunculated lipofibroma) of the eyelid. | journal = Ophthal Plast Reconstr Surg | volume = 21 | issue = 1 | pages = 74-6 | month = Jan | year = 2005 | doi = | PMID = 15677959 }}</ref> | |||
==General== | |||
*Rare. | |||
*Congenital - considered a [[hamartoma]].<ref name=pmid22984661/> | |||
*Usually young adults.<ref>URL: [http://www.dermpedia.org/dermpedia-textbook/nevus-lipomatosus http://www.dermpedia.org/dermpedia-textbook/nevus-lipomatosus]. Accessed on: 8 January 2013.</ref> | |||
Clinically separated into:<ref name=pmid17288284>{{Cite journal | last1 = Triki | first1 = S. | last2 = Mekni | first2 = A. | last3 = Haouet | first3 = S. | last4 = Mokni | first4 = M. | last5 = Kchir | first5 = N. | last6 = Ben Osman Dhahri | first6 = A. | last7 = Zitouna | first7 = M. | title = [Nevus lipomatosus cutaneous superficialis: a clinico-pathological study of 13 cases]. | journal = Tunis Med | volume = 84 | issue = 12 | pages = 800-2 | month = Dec | year = 2006 | doi = | PMID = 17288284 }}</ref> | |||
*''Solitary'' - one lesion. | |||
*''Multiple'' - more than one lesion. | |||
==Gross== | |||
Features:<ref name=pmid22984661>{{Cite journal | last1 = Goucha | first1 = S. | last2 = Khaled | first2 = A. | last3 = Zéglaoui | first3 = F. | last4 = Rammeh | first4 = S. | last5 = Zermani | first5 = R. | last6 = Fazaa | first6 = B. | title = Nevus lipomatosus cutaneous superficialis: Report of eight cases. | journal = Dermatol Ther (Heidelb) | volume = 1 | issue = 2 | pages = 25-30 | month = Dec | year = 2011 | doi = 10.1007/s13555-011-0006-y | PMID = 22984661 | PMC = 3437641 }}</ref> | |||
*Pedunculated lesion. | |||
*Soft. | |||
*Usually lower trunk or gluteal region.<ref name=pmid1235780>{{Cite journal | last1 = Jones | first1 = EW. | last2 = Marks | first2 = R. | last3 = Pongsehirun | first3 = D. | title = Naevus superficialis lipomatosus. A clinicopathological report of twenty cases. | journal = Br J Dermatol | volume = 93 | issue = 2 | pages = 121-33 | month = Aug | year = 1975 | doi = | PMID = 1235780 }}</ref> | |||
Image: | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437641/figure/Fig1/ NLS (nih.gov)].<ref name=pmid22984661/> | |||
==Microscopic== | |||
Features:<ref name=pmid19495497>{{Cite journal | last1 = Yap | first1 = FB. | title = Nevus lipomatosus superficialis. | journal = Singapore Med J | volume = 50 | issue = 5 | pages = e161-2 | month = May | year = 2009 | doi = | PMID = 19495497 | URL = http://smj.sma.org.sg/5005/5005cr3.pdf }}</ref> | |||
*Benign adipose tissue in the dermis. | |||
**Adipocytes in [[reticular dermis]] +/- [[papillary dermis]].<ref name=pmid20673540>{{Cite journal | last1 = Ghosh | first1 = SK. | last2 = Bandyopadhyay | first2 = D. | last3 = Jamadar | first3 = NS. | title = Nevus lipomatosus cutaneous superficialis: An unusual presentation. | journal = Dermatol Online J | volume = 16 | issue = 7 | pages = 12 | month = | year = 2010 | doi = | PMID = 20673540 }}</ref> | |||
DDx: | |||
*[[Lipoma]]. | |||
*[[Fibroepithelial polyp]] (skin tag). | |||
*[[Intradermal nevus]] with adipocytes.<ref name=pmid9810886>{{Cite journal | last1 = Eng | first1 = W. | last2 = Cohen | first2 = PR. | title = Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells. | journal = J Am Acad Dermatol | volume = 39 | issue = 5 Pt 1 | pages = 704-11 | month = Nov | year = 1998 | doi = | PMID = 9810886 }}</ref> | |||
===Images=== | |||
*[http://www.dermaamin.com/site/images/histo-pic/n/nevus-lipomatosus-superficialis/nevus-lipomatosus-superficialis1.jpg NLS (dermamin.com)].<ref>URL: [http://www.dermaamin.com/site/histopathology-of-the-skin/66-n/1971-nevus-lipomatosus-superficialis----.html http://www.dermaamin.com/site/histopathology-of-the-skin/66-n/1971-nevus-lipomatosus-superficialis----.html]. Accessed on: 7 March 2012.</ref> | |||
*[http://www.humpath.com/IMG/jpg/nevus_superficialis_lipomatosus_01_1.jpg NLS (humpath.com)].<ref>URL: [http://www.humpath.com/spip.php?article8134 http://www.humpath.com/spip.php?article8134]. Accessed on: 17 December 2012.</ref> | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437641/figure/Fig3/ NLS (nih.gov)].<ref name=pmid22984661/> | |||
*[http://www.dermpedia.org/dermpedia-textbook/nevus-lipomatosus Nevus lipomatosus (dermpedia.org)]. | |||
==Sign out== | |||
<pre> | |||
SKIN LESION ("SKIN TAG"), LEFT HIP, EXCISION: | |||
- NEVUS LIPOMATOSUS SUPERFICIALIS. | |||
</pre> | |||
==See also== | |||
*[[Non-malignant skin disease]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Dermatopathology]] | |||