Difference between revisions of "Littoral cell angioma"
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===Images=== | ===Images=== | ||
<gallery> | <gallery> | ||
Image:Littoral_cell_angioma_of_the_spleen_-_very_low_mag.jpg | LCA - very low mag. (WC) | Image:Littoral_cell_angioma_of_the_spleen_-_very_low_mag.jpg | LCA - very low mag. (WC) | ||
Image:Littoral_cell_angioma_of_the_spleen_-_low_mag.jpg | LCA - low mag. (WC) | |||
Image:Littoral_cell_angioma_of_the_spleen_-_intermed_mag.jpg | LCA - intermed. mag. (WC) | Image:Littoral_cell_angioma_of_the_spleen_-_intermed_mag.jpg | LCA - intermed. mag. (WC) | ||
Image:Littoral_cell_angioma_of_the_spleen_-_high_mag.jpg | LCA - high mag. (WC) | |||
Image:Littoral_cell_angioma_of_the_spleen_-_very_high_mag.jpg | LCA - very high mag. (WC) | Image:Littoral_cell_angioma_of_the_spleen_-_very_high_mag.jpg | LCA - very high mag. (WC) | ||
</gallery> | </gallery> | ||
www: | |||
*[http://www.webpathology.com/image.asp?n=5&Case=382 LCA - low mag. (webpathology.com)]. | |||
*[http://www.webpathology.com/image.asp?n=6&Case=382 LCA - high mag. (webpathology.com)]. | |||
==IHC== | ==IHC== | ||
Features:<ref name=pmid15329769/> | Features:<ref name=pmid15329769/> | ||
Revision as of 21:21, 16 February 2014
Littoral cell angioma, abbreviated LCA, is an uncommon benign vascular lesion of the spleen.
Angioma, in general, is dealt with in vascular malformations.
General
Features:[1]
- Rare.
- Benign.
- Pyrexia (fever), splenomegaly, weight loss, solitary hypodense lesion on imaging.
Note:
Microscopic
Features:[1]
- Anastoming, small vascular channels.
- Cystic spaces.
- May have papillary projections.[2]
DDx:[1]
- Vascular lesions:
Images
LCA - very low mag. (WC)
LCA - low mag. (WC)
LCA - intermed. mag. (WC)
LCA - high mag. (WC)
LCA - very high mag. (WC)
www:
IHC
Features:[1]
- CD68 +ve.
- CD31 +ve
Others:
- CD34 -ve.
- Factor VIII +ve.
See also
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Tan, YM.; Chuah, KL.; Wong, WK. (Jul 2004). "Littoral cell angioma of the spleen.". Ann Acad Med Singapore 33 (4): 524-6. PMID 15329769. http://www.annals.edu.sg/pdf200408/V33N4p524.pdf.
- ↑ 2.0 2.1 Dascalescu, CM.; Wendum, D.; Gorin, NC. (Sep 2001). "Littoral-cell angioma as a cause of splenomegaly.". N Engl J Med 345 (10): 772-3. doi:10.1056/NEJM200109063451016. PMID 11547761. http://www.nejm.org/doi/full/10.1056/NEJM200109063451016.
- ↑ URL: http://www.merriam-webster.com/dictionary/littoral. Accessed on: 24 July 2011.
- ↑ URL: http://dictionary.reference.com/browse/littoral. Accessed on: 24 July 2011.