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Intraductal papilloma of the breast (view source)
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'''Intraductal papilloma''', also '''papilloma''', is a relatively common benign [[breast pathology|pathology of the breast]]. | |||
==General== | |||
*May cause nipple discharge.<ref>{{Cite journal | last1 = Zervoudis | first1 = S. | last2 = Iatrakis | first2 = G. | last3 = Economides | first3 = P. | last4 = Polyzos | first4 = D. | last5 = Navrozoglou | first5 = I. | title = Nipple discharge screening. | journal = Womens Health (Lond Engl) | volume = 6 | issue = 1 | pages = 135-51 | month = Jan | year = 2010 | doi = 10.2217/whe.09.81 | PMID = 20050819 }}</ref> | |||
*Similar to ''[[papillary hidradenoma]]'' of the [[vulva]]. | |||
==Microscopic== | |||
Features: | |||
*True papillae - nipple-shaped structures with fibrovascular cores. | |||
*Intraductal proliferation of epithelial and myoepithelial elements.<ref name=pmid2123505>{{Cite journal | title = Adenoma of Nipple. | journal = Br Med J | volume = 1 | issue = 5330 | pages = 563 | month = Mar | year = 1963 | doi = | PMID = 20789667 | PMC = 2123505 | url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2123505/?page=1 }}</ref> | |||
Notes: | |||
*Lacks florid hyperplasia.<ref>URL: [http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html]. Accessed on: 6 August 2011.</ref> | |||
*May degeneration and hyalinize to form a ''sclerosing papilloma''. | |||
DDx: | |||
*Intraductal papilloma with [[florid epithelial hyperplasia]]. | |||
*Intraductal papilloma with [[atypical ductal hyperplasia]]. † | |||
*Intraductal papilloma with [[ductal carcinoma in situ]]. † | |||
*[[Invasive papillary carcinoma of the breast]]. | |||
† Size criteria are different in papillomas. | |||
===Images=== | |||
<gallery> | |||
Image:Papillary_hidradenoma_-_low_mag.jpg | Papillary hidradenoma - low mag. (WC/Nephron) | |||
Image:Papillary_hidradenoma_-_very_high_mag.jpg | Papillary hidradenoma - very high mag. (WC/Nephron) | |||
</gallery> | |||
==See also== | |||
*[[Breast pathology]]. | |||
*[[Papillary hidradenoma]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Breast pathology]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||