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Difference between revisions of "Electron microscopy"
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This article collection | This article is a brief collection things '''electron microscopy'''. It is commonly abbreviated '''EM'''. | ||
[[Fixation]] for EM is often done with glutaraldehyde.<ref name=pmid8787969>{{Cite journal | last1 = Prentø | first1 = P. | title = Glutaraldehyde for electron microscopy: a practical investigation of commercial glutaraldehydes and glutaraldehyde-storage conditions. | journal = Histochem J | volume = 27 | issue = 11 | pages = 906-13 | month = Nov | year = 1995 | doi = | PMID = 8787969 }}</ref> | |||
=Ultrastructural findings= | =Ultrastructural findings= | ||
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*Found in epithelial cells. | *Found in epithelial cells. | ||
*Part of the cytoskeleton. | *Part of the cytoskeleton. | ||
*May be found in the epithelioid component of a biphasic [[synovial sarcoma]].<ref name=pmid9930576>{{Cite journal | last1 = Fisher | first1 = C. | title = Synovial sarcoma. | journal = Ann Diagn Pathol | volume = 2 | issue = 6 | pages = 401-21 | month = Dec | year = 1998 | doi = | PMID = 9930576 }}</ref> | |||
===Ultrastructure=== | ===Ultrastructure=== | ||
Features: | |||
*Filamentous structures at the cell periphery - vaguely resemble striated muscle. | *Filamentous structures at the cell periphery - vaguely resemble striated muscle. | ||
Image(s): | Image(s): | ||
*[http://www.bioscience.org/atlases/tumpath/em/tonofila.htm Tonofilaments (bioscience.org)]. | *[http://www.bioscience.org/atlases/tumpath/em/tonofila.htm Tonofilaments (bioscience.org)]. | ||
==Zymogen granules== | |||
===General=== | |||
*Seen in [[acinic cell carcinoma]]. | |||
*[[Pancreas]] - acinar cell.<ref name=pmid11030603>{{Cite journal | last1 = Gorelick | first1 = FS. | last2 = Otani | first2 = T. | title = Mechanisms of intracellular zymogen activation. | journal = Baillieres Best Pract Res Clin Gastroenterol | volume = 13 | issue = 2 | pages = 227-40 | month = Jul | year = 1999 | doi = | PMID = 11030603 }} | |||
</ref> | |||
===Ultrastructure=== | |||
Features: | |||
*Round structures ~0.5-1.5 μm. | |||
Images: | |||
*[http://db2.photoresearchers.com/preview/9C3411.html Zymogen granules (photoresearchers.com)]. | |||
*[http://www3.mpibpc.mpg.de/groups/em/Gallery/Pnacreas/158wt1.jpg Zymogen granules (mpg.de)].<ref>URL: [http://www3.mpibpc.mpg.de/groups/em/Gallery.htm http://www3.mpibpc.mpg.de/groups/em/Gallery.htm]. Accessed on: 1 June 2012.</ref> | |||
=Specific diagnoses= | =Specific diagnoses= | ||