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Difference between revisions of "Neuropathology tumours"
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Neuropathology tumours (view source)
Revision as of 04:03, 23 November 2010
, 04:03, 23 November 2010→Microscopy
(→Atypical teratoid/rhabdoid tumour: tweak) |
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DDx (classic ependymoma): | DDx (classic ependymoma): | ||
*Subependymoma. | *Subependymoma. | ||
*Glioblastoma (GBM). | |||
**Invasive border = GBM; circumscribed border of lesion = ependymoma. | |||
====Myxopapillary ependymoma==== | ====Myxopapillary ependymoma==== | ||
| Line 329: | Line 331: | ||
*[http://careers.bmj.com/article-images/cf0708.f2_default.gif Myxopapillary ependymoma (bmj.com)] - part of [http://careers.bmj.com/careers/advice/view-article.html?id=351 careers.bmj.com article on paediatric pathology]. | *[http://careers.bmj.com/article-images/cf0708.f2_default.gif Myxopapillary ependymoma (bmj.com)] - part of [http://careers.bmj.com/careers/advice/view-article.html?id=351 careers.bmj.com article on paediatric pathology]. | ||
*[http://commons.wikimedia.org/wiki/File:Myxopapillary_ependymoma.jpg Myxopapillary ependymoma - cytology (WC)]. | *[http://commons.wikimedia.org/wiki/File:Myxopapillary_ependymoma.jpg Myxopapillary ependymoma - cytology (WC)]. | ||
====Grading==== | |||
Easy: | |||
*Subependymoma = WHO grade I. | |||
*Myxopapillary ependymoma = WHO grade I. | |||
Not-so-easy: | |||
*Classic ependymoma = WHO grade II. | |||
*Anaplastic ependymoma = WHO grade III. | |||
Grade II vs. Grade III: | |||
*Cellular density. | |||
*Mitoses. | |||
*Necrosis. | |||
*Microvascular proliferation. | |||
Notes: | |||
*Many tumours fall between grade II and grade III. These are called "indeterminate" by many. | |||
===IHC=== | |||
*Reticulin. | |||
*GFAP. | |||
*MIB-1. | |||
==Choroid plexus papilloma== | ==Choroid plexus papilloma== | ||