Difference between revisions of "Granular cell tumour"

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Revision as of 05:46, 19 November 2010

The granular cell tumour is a rare beast.

General

  • Rare.
  • Usually benign.

Gross

  • Yellow nodule.

Note:

  • DDx of yellow nodule: granular cell tumour, lipoma, xanthoma.

Microscopic

Features:

  • Abundant eosinophilic granular cytoplasm.
    • Granules 1-3 micrometers in size.

Special stains

  • PAS +ve.

IHC

Features:[1]

  • S100 +ve.
  • CD68 +ve (cytoplasmic).
  • Vimentin +ve (membranous).

Images:

See also

References

  1. Rekhi, B.; Jambhekar, NA. (Jun 2010). "Morphologic spectrum, immunohistochemical analysis, and clinical features of a series of granular cell tumors of soft tissues: a study from a tertiary referral cancer center.". Ann Diagn Pathol 14 (3): 162-7. doi:10.1016/j.anndiagpath.2010.01.005. PMID 20471560.