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Intestinal spirochetosis (view source)
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'''Intestinal spirochetosis''', also known as '''intestinal spirochetes''', in an uncommon intestinal infection. | |||
It is usually in the [[colon]]; thus, also known as '''colonic spirochetes''' and '''colonic spirochetosis'''. | |||
==General== | |||
*Caused by spirochetes<ref name=pmid14718105>{{cite journal |author=Amat Villegas I, Borobio Aguilar E, Beloqui Perez R, de Llano Varela P, Oquiñena Legaz S, Martínez-Peñuela Virseda JM |title=[Colonic spirochetes: an infrequent cause of adult diarrhea] |language=Spanish; Castilian |journal=Gastroenterol Hepatol |volume=27 |issue=1 |pages=21–3 |year=2004 |month=January |pmid=14718105 |doi= |url=}}</ref><ref name=jhasim>URL: [http://www.jhasim.com/files/articlefiles/pdf/XASIM_Master_6_5_May_Vignette.pdf http://www.jhasim.com/files/articlefiles/pdf/XASIM_Master_6_5_May_Vignette.pdf]. Accessed on: 25 April 2011.</ref> - specifically ''Brachyspira piloicoli''<ref name=pmid19141744>{{Cite journal | last1 = Margawani | first1 = KR. | last2 = Robertson | first2 = ID. | last3 = Hampson | first3 = DJ. | title = Isolation of the anaerobic intestinal spirochaete Brachyspira pilosicoli from long-term residents and Indonesian visitors to Perth, Western Australia. | journal = J Med Microbiol | volume = 58 | issue = Pt 2 | pages = 248-52 | month = Feb | year = 2009 | doi = 10.1099/jmm.0.004770-0 | PMID = 19141744 | url = http://ukpmc.ac.uk/abstract/MED/19141744/abstract/MED/19141744?ukpmc_extredirect=http://dx.doi.org/10.1099/jmm.0.004770-0 }}</ref> (previously ''Serpulina pilosicoli''<ref>URL: [http://www.cdc.gov/ncidod/eid/vol12no05/05-1180.htm http://www.cdc.gov/ncidod/eid/vol12no05/05-1180.htm]. Accessed on: 28 June 2011.</ref>) and ''Brachyspira aalborgi''. | |||
*Very rare cause of diarrhea, associated with male homosexual behaviour. | |||
Symptoms:<ref name=jhasim>URL: [http://www.jhasim.com/files/articlefiles/pdf/XASIM_Master_6_5_May_Vignette.pdf http://www.jhasim.com/files/articlefiles/pdf/XASIM_Master_6_5_May_Vignette.pdf]. Accessed on: 25 April 2011.</ref> | |||
*Watery diarrhea, abdominal pain, +/-blood per rectum. | |||
Treatment:<ref name=pmid17914949>{{cite journal |author=Calderaro A, Bommezzadri S, Gorrini C, ''et al.'' |title=Infective colitis associated with human intestinal spirochetosis |journal=J. Gastroenterol. Hepatol. |volume=22 |issue=11 |pages=1772–9 |year=2007 |month=November |pmid=17914949 |doi=10.1111/j.1440-1746.2006.04606.x |url=}}</ref> | |||
*Metronidazole. | |||
==Microscopic== | |||
Features: | |||
*Hyperchromatic fuzz on luminal aspect of epithelial cells; at brush border. | |||
DDx: | |||
*Normal colon. | |||
*[[Infectious colitis]] without a distinctive morphology. | |||
===Images=== | |||
<gallery> | |||
Image:Intestinal_spirochetosis_-_cropped_-_very_high_mag.jpg | Intestinal spirochetes - cropped - very high mag. (WC/Nephron) | |||
Image:Intestinal_spirochetosis_-_very_high_mag.jpg | Intestinal spirochetes - very high mag. (WC/Nephron) | |||
Image:Intestinal_spirochetosis_-_intermed_mag.jpg | Intestinal spirochetes - intermed. mag. (WC/Nephron) | |||
</gallery> | |||
www: | |||
*[http://path.upmc.edu/cases/case391.html Intestinal spirochetosis & CMV colitis - several images (upmc.edu)]. | |||
==Special stains== | |||
*Silver stains highlight 'em (e.g. [[Warthin-Starry stain]]). | |||
==See also== | |||
*[[Colon]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Colon]] | |||