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| Caption = Contraction band necrosis - a finding of MI. [[H&E stain]]. | | Caption = Contraction band necrosis - a finding of MI. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = wavy fibers, myocyte [[necrosis]] with loss of cross striations, [[contraction band necrosis|contraction bands]], edema, hemorrhage, neutrophilic infiltrate, pyknosis of nuclei, loss of nuclei (karyolysis) | | Micro = early to late: wavy fibers, myocyte [[necrosis]] with loss of cross striations, [[contraction band necrosis|contraction bands]], edema, hemorrhage, neutrophilic infiltrate, pyknosis of nuclei, loss of nuclei (karyolysis), macrophage and mononuclear infiltration, fibrovascular response, [[granulation tissue]], myocardial fibrosis | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[cardiac amyloidosis]] for old infarct, [[myocarditis]] | | LMDDx = [[cardiac amyloidosis]] for old infarct, [[myocarditis]] | ||
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| Molecular = | | Molecular = | ||
| IF = | | IF = | ||
| Gross = myocardial pallor, hyperemia (redness), yellow lesion with hyperemic border, white (fibrosis) | | Gross = early to late: myocardial pallor, hyperemia (redness), yellow lesion with hyperemic border, white (fibrosis) | ||
| Grossing = | | Grossing = | ||
| Site = [[heart]] | | Site = [[heart]] | ||
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| Prognosis = dependent on extent | | Prognosis = dependent on extent | ||
| Other = | | Other = | ||
| ClinDDx = varies by presentation - usu. [[aortic dissection]], [[acute pneumonia]], [[pulmonary embolism]], GI pathology, | | ClinDDx = varies by presentation - usu. [[aortic dissection]], [[acute infectinous pneumonia]], [[pulmonary embolism]], GI pathology, | ||
| Tx = | | Tx = | ||
}} | }} |
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