Difference between revisions of "Chiari malformation"
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Revision as of 21:12, 2 January 2014
Chiari malformation is a developmental abnormality of the brain.
General
- Usually a radiologic diagnosis.
- May be seen in a fetal autopsy.
Clinical:[1]
- Headaches, occipital.
- Dizziness.
- Nocturnal respiratory abnormalities.
Classification
Numbered from least severe to most severe:
- Chiari type I - tonsils herniated[2] (radiologic definition: 4-6 mm below the plane of the foramen magnum).
- Associated with: sudden death,[3] sleep apnea, cerebellar ataxia.
- Chiari type II - often assoc. with hydrocephaly at birth.
- Chiari type III - cerebellum + brain stem herniate through foramen magnum +/- encephalocele.[4]
- Chiari type IV - cerebellar hypoplasia or no cerebellum.
See also
References
- ↑ Ferré Masó, A.; Poca, MA.; de la Calzada, MD.; Solana, E.; Romero Tomás, O.; Sahuquillo, J. (Mar 2011). "Sleep disturbance: a forgotten syndrome in patients with Chiari I malformation.". Neurologia. doi:10.1016/j.nrl.2011.01.008. PMID 21420201.
- ↑ URL: http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230. Accessed on: 6 May 2011.
- ↑ Zhang, J.; Shao, Y.; Qin, Z.; Liu, N.; Zou, D.; Huang, P.; Chen, Y. (Dec 2012). "Sudden Unexpected Death due to Chiari Type I Malformation in a Road Accident Case.". J Forensic Sci. doi:10.1111/1556-4029.12051. PMID 23278920.
- ↑ URL: http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm. Accessed on: 6 May 2011.