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Difference between revisions of "Autoimmune hepatitis"
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| Assdx = | | Assdx = | ||
| Syndromes = | | Syndromes = | ||
| Clinicalhx = | | Clinicalhx = usu. women - young or middle-aged | ||
| Signs = | | Signs = | ||
| Symptoms = | | Symptoms = | ||
| Line 24: | Line 24: | ||
| Rads = | | Rads = | ||
| Endoscopy = | | Endoscopy = | ||
| Prognosis = | | Prognosis = poor without treatment | ||
| Other = | | Other = | ||
| ClinDDx = [[primary biliary cirrhosis]], [[primary sclerosing cholangitis]] | | ClinDDx = [[primary biliary cirrhosis]], [[primary sclerosing cholangitis]] | ||
| Tx = corticosteroids, immunosuppression, liver transplant (end stage) | |||
}} | }} | ||
'''Autoimmune hepatitis''', abbreviated '''AIH''', in an uncommon [[medical liver disease]] that occurs in adults and children. | '''Autoimmune hepatitis''', abbreviated '''AIH''', in an uncommon [[medical liver disease]] that occurs in adults and children. | ||
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==General== | ==General== | ||
*Several criteria exist to diagnose and histology (alone) is '''not''' sufficient. | *Several criteria exist to diagnose and histology (alone) is '''not''' sufficient. | ||
*Classically, young and middle aged women.<ref name=pmid24367228>{{Cite journal | last1 = Francque | first1 = S. | last2 = Vonghia | first2 = L. | last3 = Ramon | first3 = A. | last4 = Michielsen | first4 = P. | title = Epidemiology and treatment of autoimmune hepatitis. | journal = Hepat Med | volume = 4 | issue = | pages = 1-10 | month = | year = 2012 | doi = 10.2147/HMER.S16321 | PMID = 24367228 }}</ref> | |||
**May occur in men. | |||
*Often a fluctuating course. | |||
*Untreated AIH has a poor outcome.<ref name=pmid24367228/> | |||
**Leads to [[cirrhosis]] and liver failure. | |||
Treatment:<ref name=pmid24367228/> | |||
*Corticosteroids, immunosuppression. | |||
*Liver transplant (end-stage disease). | |||
===Diagnosis=== | ===Diagnosis=== | ||