Difference between revisions of "Talk:Bone"
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==Aneurysmal bone cyst== | ==Aneurysmal bone cyst== | ||
===Microscopic description=== | ===Microscopic description=== | ||
The sections show cartilage, bone and osteoid with variable mineralization surrounded by fibroblasts, hemosiderin-laden macrophages, and multi-nucleated giant-cells with | The sections show cartilage, bone and osteoid with variable mineralization surrounded by fibroblasts, hemosiderin-laden macrophages, and multi-nucleated giant-cells with randomly arranged, round nuclei. Hemosiderin-laden macrophages are seen focally. There is no nuclear atypia or mitotic activity. There is no malignant appearing osteoid. | ||
===Final diagnosis=== | ===Final diagnosis=== | ||
Humerous, right proximal, excision - Aneurysmal bone cyst. | Humerous, right proximal, excision - Aneurysmal bone cyst. | ||
== Burnt-out chronic osteomyelitis == | |||
<pre> | |||
GREAT TOE, LEFT, AMPUTATION: | |||
- SKIN WITH ULCERATION AND IMPETIGINIZATION. | |||
- ATHEROSCLEROSIS, MODERATE-TO-SEVERE. | |||
- SOFT TISSUE WITH FIBROSIS AND CHRONIC INFLAMMATION. | |||
- BONE AND MILDLY FIBROTIC MARROW SPACE WITH SCATTERED LYMPHOCYTES AND SIDEROPHAGES; | |||
NO SIGNIFICANT NUMBERS OF PLASMA CELLS OR NEUTROPHILS APPARENT. | |||
- NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
== Osteoporosis == | |||
Note: | |||
*There isn't a number for "thin" trabeculae. Anecdotally, I suspect "thin" is 0.15-0.2 mm. | |||
**Crude guess at normal thickness is ~ 0.4 mm. [1] | |||
1. {{Cite journal | last1 = Klintström | first1 = E. | last2 = Smedby | first2 = O. | last3 = Moreno | first3 = R. | last4 = Brismar | first4 = TB. | title = Trabecular bone structure parameters from 3D image processing of clinical multi-slice and cone-beam computed tomography data. | journal = Skeletal Radiol | volume = | issue = | pages = | month = Nov | year = 2013 | doi = 10.1007/s00256-013-1766-5 | PMID = 24271010 }} | |||
Latest revision as of 12:48, 23 December 2013
Aneurysmal bone cyst
Microscopic description
The sections show cartilage, bone and osteoid with variable mineralization surrounded by fibroblasts, hemosiderin-laden macrophages, and multi-nucleated giant-cells with randomly arranged, round nuclei. Hemosiderin-laden macrophages are seen focally. There is no nuclear atypia or mitotic activity. There is no malignant appearing osteoid.
Final diagnosis
Humerous, right proximal, excision - Aneurysmal bone cyst.
Burnt-out chronic osteomyelitis
GREAT TOE, LEFT, AMPUTATION: - SKIN WITH ULCERATION AND IMPETIGINIZATION. - ATHEROSCLEROSIS, MODERATE-TO-SEVERE. - SOFT TISSUE WITH FIBROSIS AND CHRONIC INFLAMMATION. - BONE AND MILDLY FIBROTIC MARROW SPACE WITH SCATTERED LYMPHOCYTES AND SIDEROPHAGES; NO SIGNIFICANT NUMBERS OF PLASMA CELLS OR NEUTROPHILS APPARENT. - NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY.
Osteoporosis
Note:
- There isn't a number for "thin" trabeculae. Anecdotally, I suspect "thin" is 0.15-0.2 mm.
- Crude guess at normal thickness is ~ 0.4 mm. [1]
1. Klintström, E.; Smedby, O.; Moreno, R.; Brismar, TB. (Nov 2013). "Trabecular bone structure parameters from 3D image processing of clinical multi-slice and cone-beam computed tomography data.". Skeletal Radiol. doi:10.1007/s00256-013-1766-5. PMID 24271010.