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Pigmented spindle cell nevus (view source)
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'''Pigmented spindle cell nevus''', also '''pigmented spindle cell nevus of Reed''', is an uncommon benign [[melanocytic lesion]]. | |||
==General== | |||
*Uncommon. | |||
*Women in teens & 20s. | |||
==Gross== | |||
*Location: shoulder, pelvic girdle region. | |||
==Microscopic== | |||
Features:<ref name=Ref_WMSP500>{{Ref WMSP|500}}</ref> | |||
*Nests of heavily pigmented spindle cells at dermal-epidermal junction - '''key feature'''. | |||
**Nevoid cells in epidermis & dermis - form "basket weave" pattern | |||
*Well-circumscribed lesion. | |||
Notes: | |||
*No epithelioid nevus cells. | |||
DDx: | |||
*[[Spitz nevus]]. | |||
*[[Malignant melanoma]]. | |||
===Images=== | |||
<gallery> | |||
Image:Pigmented_spindle_cell_nevus_-_low_mag.jpg | PSCN - low mag. (WC) | |||
Image:Pigmented_spindle_cell_nevus_-_2_-_intermed_mag.jpg | PSCN - intermed. mag. (WC) | |||
Image:Pigmented_spindle_cell_nevus_-_2_-_high_mag.jpg | PSCN - high mag. (WC) | |||
</gallery> | |||
www: | |||
*[http://www.histopathology-india.net/Reed.htm Reed nevus - collection (histopathology-india.net)]. | |||
==Sign out== | |||
<pre> | |||
SKIN LESION, RIGHT POSTERIOR NECK, EXCISION: | |||
- PIGMENTED SPINDLE CELL NEVUS OF REED. | |||
-- COMPLETELY EXCISED (CLEARANCE ~ 1 MM). | |||
</pre> | |||
===Micro=== | |||
The sections show spindled pigmented melanocytes in nests confined to the epidermis. | |||
The lesion is symmetrical in its architecture and pigment distribution. There is no | |||
pagetoid spread of melanocytes in the epidermis. No significant nuclear atypia is | |||
identified. No mitotic activity is appreciated. Melanophages are present in the superficial | |||
dermis. The lesion is completely excised in the plane of section. | |||
==See also== | |||
*[[Melanocytic lesions]]. | |||
*[[Spitz nevus]]. | |||
*[[Malignant melanoma]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Melanocytic lesions]] | |||