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'''Xanthogranulomatous cholecystitis''', abbreviated '''XGC''', is an uncommon pathology of the [[gallbladder]]. | '''Xanthogranulomatous cholecystitis''', abbreviated '''XGC''', is an uncommon pathology of the [[gallbladder]]. | ||
==General== | |||
*Uncommon ~ 1-9%.<ref name=pmid23991684>{{Cite journal | last1 = Hale | first1 = MD. | last2 = Roberts | first2 = KJ. | last3 = Hodson | first3 = J. | last4 = Scott | first4 = N. | last5 = Sheridan | first5 = M. | last6 = Toogood | first6 = GJ. | title = Xanthogranulomatous cholecystitis: a European and global perspective. | journal = HPB (Oxford) | volume = | issue = | pages = | month = Aug | year = 2013 | doi = 10.1111/hpb.12152 | PMID = 23991684 }}</ref><ref name=pmid24019688>{{Cite journal | last1 = Alvi | first1 = AR. | last2 = Jalbani | first2 = I. | last3 = Murtaza | first3 = G. | last4 = Hameed | first4 = A. | title = Outcomes of Xanthogranulomatous cholecystitis in laparoscopic era: A retrospective Cohort study. | journal = J Minim Access Surg | volume = 9 | issue = 3 | pages = 109-15 | month = Jul | year = 2013 | doi = 10.4103/0972-9941.115368 | PMID = 24019688 }}</ref> | *Uncommon ~ 1-9%.<ref name=pmid23991684>{{Cite journal | last1 = Hale | first1 = MD. | last2 = Roberts | first2 = KJ. | last3 = Hodson | first3 = J. | last4 = Scott | first4 = N. | last5 = Sheridan | first5 = M. | last6 = Toogood | first6 = GJ. | title = Xanthogranulomatous cholecystitis: a European and global perspective. | journal = HPB (Oxford) | volume = | issue = | pages = | month = Aug | year = 2013 | doi = 10.1111/hpb.12152 | PMID = 23991684 }}</ref><ref name=pmid24019688>{{Cite journal | last1 = Alvi | first1 = AR. | last2 = Jalbani | first2 = I. | last3 = Murtaza | first3 = G. | last4 = Hameed | first4 = A. | title = Outcomes of Xanthogranulomatous cholecystitis in laparoscopic era: A retrospective Cohort study. | journal = J Minim Access Surg | volume = 9 | issue = 3 | pages = 109-15 | month = Jul | year = 2013 | doi = 10.4103/0972-9941.115368 | PMID = 24019688 }}</ref> | ||
*May be confused with [[gallbladder carcinoma]].<ref name=pmid23991684/> | *May be confused with [[gallbladder carcinoma]].<ref name=pmid23991684/> | ||
===Microscopic | ==Gross== | ||
Features:<ref name=pmid23726123>{{Cite journal | last1 = Zhao | first1 = F. | last2 = Lu | first2 = PX. | last3 = Yan | first3 = SX. | last4 = Wang | first4 = GF. | last5 = Yuan | first5 = J. | last6 = Zhang | first6 = SZ. | last7 = Wang | first7 = YX. | title = CT and MR features of xanthogranulomatous cholecystitis: an analysis of consecutive 49 cases. | journal = Eur J Radiol | volume = 82 | issue = 9 | pages = 1391-7 | month = Sep | year = 2013 | doi = 10.1016/j.ejrad.2013.04.026 | PMID = 23726123 }}</ref> | |||
*Wall thickening ~ 90% of cases. | |||
*Gallstones ~ 70% of cases. | |||
*+/-Infiltration of surrounding tissues (liver, fat). | |||
Imaging: | |||
*Hypo-attenuated nodules in the gallbladder wall.<ref name=pmid23726123/> | |||
==Microscopic== | |||
Features: | Features: | ||
*Cholesterol clefts. | *Cholesterol clefts. |
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