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Difference between revisions of "TFE3-rearranged renal cell carcinoma"
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TFE3-rearranged renal cell carcinoma (view source)
Revision as of 16:24, 23 November 2013
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Xp11.2_translocation_renal_cell_carcinoma_-_high_mag.jpg | |||
| Width = | |||
| Caption = Xp11.2 translocation carcinoma. [[H&E stain]]. | |||
| Micro = large cells with clear or eosinophilic cytoplasm, calcification (classic histomorphologic feature), +/-papillae, +/-nests, +/-[[psammoma bodies]] (common), +/-[[hyaline bodies]] (common) | |||
| Subtypes = | |||
| LMDDx = [[clear cell renal cell carcinoma]], [[papillary renal cell carcinoma]], [[epithelioid angiomyolipoma]], [[clear cell papillary renal cell carcinoma]] | |||
| Stains = | |||
| IHC = TFE3 +ve (nucleus), CD10 +ve, vimentin +ve, CK7 -ve (usu.) | |||
| EM = | |||
| Molecular = [[translocation]] involving TFE3, e.g. t(X;1)(p11.2;q21) | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[kidney]] - see [[kidney tumours]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = rare | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = poor | |||
| Other = | |||
| ClinDDx = other [[kidney tumours]] | |||
}} | |||
'''Renal tumour with Xp11.2 translocation''', also '''Xp11.2 translocation carcinoma''', is an uncommon [[malignant]] [[kidney tumour]]. | '''Renal tumour with Xp11.2 translocation''', also '''Xp11.2 translocation carcinoma''', is an uncommon [[malignant]] [[kidney tumour]]. | ||