Schmorl's node: Difference between revisions
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Image:Roe-schmorl.jpg | Schmorl's node. (WC) | Image:Roe-schmorl.jpg | Schmorl's node. (WC) | ||
</gallery> | </gallery> | ||
DDx - radiologic: | |||
*[[Plasma cell neoplasm]]. | |||
*Metastatic carcinoma. | |||
==Microscopic== | |||
Features:<ref name=pmid12931811>{{Cite journal | last1 = Peng | first1 = B. | last2 = Wu | first2 = W. | last3 = Hou | first3 = S. | last4 = Shang | first4 = W. | last5 = Wang | first5 = X. | last6 = Yang | first6 = Y. | title = The pathogenesis of Schmorl's nodes. | journal = J Bone Joint Surg Br | volume = 85 | issue = 6 | pages = 879-82 | month = Aug | year = 2003 | doi = | PMID = 12931811 | URL = http://www.bjj.boneandjoint.org.uk/content/85-B/6/879.long }}</ref> | |||
*Subchondral [[necrosis]] of bone - '''key feature'''. | |||
**Loss of osteocytes within the bony trabeculae. | |||
*Reactive [[woven bone]]: | |||
**Thickened trabeculae. | |||
**Increased numbers of osteoblasts and osteoclasts. | |||
*Bone marrow cavity fibrosis with small blood vessels and loss of adipocytes (reactive process). | |||
Note: | |||
*Histologically, ''Schmorl's node'' is considered a cousin of [[avascular necrosis of the femoral head]].<ref name=pmid12931811/> | |||
==Sign out== | |||
<pre> | |||
LESION, L4 VERTEBRA, BIOPSY: | |||
- BENIGN BONE AND BONE MARROW. | |||
- NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
===Micro=== | |||
The sections show woven bone with slightly thickened bony trabeculae. Bone with some empty | |||
lacunae is seen focally. A small amount of benign fibrotic tissue with small blood vessels | |||
is present. The bone marrow present has all three lineages. No atypical cells are apparent. | |||
==See also== | ==See also== | ||
*[[Spine]]. | *[[Spine]]. | ||
*[[Necrosis]]. | |||
==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||