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Difference between revisions of "Osteoarthritis"
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*Cartilaginous calcification is seen with OA; however, it is thought to be due to aging.<ref name=pmid17276093>{{Cite journal | last1 = Mitsuyama | first1 = H. | last2 = Healey | first2 = RM. | last3 = Terkeltaub | first3 = RA. | last4 = Coutts | first4 = RD. | last5 = Amiel | first5 = D. | title = Calcification of human articular knee cartilage is primarily an effect of aging rather than osteoarthritis. | journal = Osteoarthritis Cartilage | volume = 15 | issue = 5 | pages = 559-65 | month = May | year = 2007 | doi = 10.1016/j.joca.2006.10.017 | PMID = 17276093 }}</ref> | *Cartilaginous calcification is seen with OA; however, it is thought to be due to aging.<ref name=pmid17276093>{{Cite journal | last1 = Mitsuyama | first1 = H. | last2 = Healey | first2 = RM. | last3 = Terkeltaub | first3 = RA. | last4 = Coutts | first4 = RD. | last5 = Amiel | first5 = D. | title = Calcification of human articular knee cartilage is primarily an effect of aging rather than osteoarthritis. | journal = Osteoarthritis Cartilage | volume = 15 | issue = 5 | pages = 559-65 | month = May | year = 2007 | doi = 10.1016/j.joca.2006.10.017 | PMID = 17276093 }}</ref> | ||
===Grading=== | |||
A grading system exists from ''Pritzker'' and colleagues:<ref name=pmid16242352>{{Cite journal | last1 = Pritzker | first1 = KP. | last2 = Gay | first2 = S. | last3 = Jimenez | first3 = SA. | last4 = Ostergaard | first4 = K. | last5 = Pelletier | first5 = JP. | last6 = Revell | first6 = PA. | last7 = Salter | first7 = D. | last8 = van den Berg | first8 = WB. | title = Osteoarthritis cartilage histopathology: grading and staging. | journal = Osteoarthritis Cartilage | volume = 14 | issue = 1 | pages = 13-29 | month = Jan | year = 2006 | doi = 10.1016/j.joca.2005.07.014 | PMID = 16242352 }}</ref> | |||
{| class="wikitable sortable" | |||
! Grade | |||
! Key feature | |||
! Additional findings | |||
|- | |||
| Grade 0 (normal) | |||
| surface intact | |||
| normal thickness | |||
|- | |||
| Grade 1 | |||
| surface intact, surface fibrillation | |||
| soft tissue cellular proliferation (clustering) | |||
|- | |||
| Grade 2 | |||
| discontinous surface (diffuse superficial fibrillation or surface abrasions) | |||
| +/-chondron columns disoriented | |||
|- | |||
| Grade 3 | |||
| vertical fissures (simple or branched) | |||
| +/-new collagen formation (seen with polarized light) | |||
|- | |||
| Grade 4 | |||
| erosion (cartilage loss) | |||
| +/- cartilageous cyst formation | |||
|- | |||
| Grade 5 | |||
| complete cartilage loss | |||
| no deformation | |||
|- | |||
| Grade 6 | |||
| deformed bone (osteophytes peripheral or central) | |||
| +/-deformation of articular surface +/-microfractures | |||
|} | |||
===Images=== | ===Images=== | ||