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Difference between revisions of "Neuropathology"
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==Histopathology== | ==Histopathology== | ||
===Astrocyte changes=== | |||
Reactive astrocytes. | |||
*Eosinophilic cytoplasm. | |||
*Peripheral nucleus. | |||
*Well-defined cell border. | |||
*Many branching processes. | |||
Alzheimer type II | ====Types==== | ||
*Large cleared | Alzheimer type II astrocyte:<ref>URL: [http://www.neuropathologyweb.org/chapter1/chapter1bAstrocytes.html http://www.neuropathologyweb.org/chapter1/chapter1bAstrocytes.html]. Accessed on: 2 July 2010.</ref> | ||
*Large cleared nucleus - '''key feature'''. | |||
*Indistinct cytoplasm. | *Indistinct cytoplasm. | ||
*Images: | *Images: | ||
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**[http://www.neuropathologyweb.org/chapter10/images10/10-AlzIIl.jpg Alzheimer type II astrocytes (neuropathologyweb.org)] . | **[http://www.neuropathologyweb.org/chapter10/images10/10-AlzIIl.jpg Alzheimer type II astrocytes (neuropathologyweb.org)] . | ||
*Axonal swellings | Bergmann gliosis (in the cerebellum):<ref name=Ref_PSNP18>{{Ref PSNP|18}}</ref> | ||
*Thin layer of cells (2-3 cells), nuclei open and larger than granular cell layer nuclei. | |||
**Image: [http://tpx.sagepub.com/content/35/5/676/F5.expansion.html Bergmann gliosis (sagepub.com)]. | |||
Creutzfeldt cell:<ref name=Ref_PSNP18>{{Ref PSNP|18}}</ref> | |||
*Astrocyte that mimics a mitoses; has moderate (identifiable) cytoplasm. | |||
*Finding associated with demyelinating disease. | |||
===Other=== | |||
Axonal swellings: | |||
*Image: [http://www.neuropathologyweb.org/chapter3/images3/3-pvlaxonsweling.jpg Axonal swelling] - neuropathologyweb.org. | |||
===Architecture=== | ===Architecture=== | ||