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Difference between revisions of "Granular cell tumour"
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Granular cell tumour (view source)
Revision as of 15:05, 28 September 2013
, 15:05, 28 September 2013+infobox
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Granular_cell_tumor_(3)_skin.jpg | |||
| Width = | |||
| Caption = Granular cell tumour. [[H&E stain]]. | |||
| Micro = cells with abundant eosinophilic granular cytoplasm (granules ~ 1-3 micrometers, poorly demarcated on LM), +/-[[pseudoepitheliomatous hyperplasia]] | |||
| Subtypes = | |||
| LMDDx = [[squamous cell carcinoma]], [[oncocytoma]], adjacent ulcer | |||
| Stains = PAS +ve | |||
| IHC = S-100 +ve, CD68 +ve (cytoplasmic), vimentin +ve (membranous), calretinin +ve (usually) | |||
| EM = abundant lysosomes | |||
| Molecular = | |||
| IF = | |||
| Gross = yellow nodule | |||
| Grossing = | |||
| Site = typically [[head and neck pathology|head and neck]] - other sites: [[breast]], [[skin]], tongue, [[esophagus]] + more | |||
| Assdx = | |||
| Syndromes = [[LEOPARD syndrome]] | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = rare | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = usu. benign, may be malignant | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
The '''granular cell tumour''' is a rare histomorphologically distinctive neoplasm found at many sites. The classic location is the head and neck. | The '''granular cell tumour''' is a rare histomorphologically distinctive neoplasm found at many sites. The classic location is the head and neck. | ||