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Difference between revisions of "Keloid"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Keloid_-_add_-_intermed_mag.jpg | |||
| Width = | |||
| Caption = Keloid. [[H&E stain]]. | |||
| Micro = thick collagen bundles - surrounded by paler staining fibroblasts, loss of adnexal structures | |||
| Subtypes = | |||
| LMDDx = hypertrophic scar | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[skin]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = typically dark skinned individuals | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
:''Hypertrophic scar'' redirects here. | |||
'''Keloid''' is an uncommon abnormal [[scar|scarring]]. | |||
==General== | |||
*Sites of previous trauma/surgery, esp. in dark skinned individuals.<ref name=Ref_WMSP492>{{Ref WMSP|492}}</ref> | |||
Note: | |||
*'''Reported as "keloidal-type collagen"'''; the clinician decides between ''hypertrophic scar'' and ''keloid''. | |||
==Microscopic== | |||
Features:<ref name=Ref_WMSP492>{{Ref WMSP|492}}</ref> | |||
*Thick collagen bundles - surrounded by paler staining fibroblasts - '''key feature'''. | |||
*Lesion replaces adnexal structures, e.g. hair, sweat glands. | |||
DDx: | |||
*Hypertrophic scar.<ref name=pmid20927486>{{Cite journal | last1 = Gauglitz | first1 = GG. | last2 = Korting | first2 = HC. | last3 = Pavicic | first3 = T. | last4 = Ruzicka | first4 = T. | last5 = Jeschke | first5 = MG. | title = Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies. | journal = Mol Med | volume = 17 | issue = 1-2 | pages = 113-25 | month = | year = | doi = 10.2119/molmed.2009.00153 | PMID = 20927486 | PMC = 3022978 }}</ref> | |||
===Images=== | |||
<gallery> | |||
Image:Keloid_-_add_-_low_mag.jpg | Keloid - low mag. (WC/Nephron) | |||
Image:Keloid_-_add_-_intermed_mag.jpg | Keloid - intermed. mag. (WC/Nephron) | |||
Image:Keloid_-_high_mag.jpg | Keloid - high mag. (WC/Nephron) | |||
</gallery> | |||
www: | |||
*[http://missinglink.ucsf.edu/lm/DermatologyGlossary/keloids.html Keloid (ucsf.edu)]. | |||
==Sign out== | |||
<pre> | |||
SKIN LESION, LEFT SCAPULA, EXCISION: | |||
- DERMAL SCAR WITH KELOIDAL-TYPE COLLAGEN, SEE COMMENT. | |||
COMMENT: | |||
The findings are consistent with a hypertrophic scar or keloid; clinical correlation is required. | |||
</pre> | |||
===Clinical provided=== | |||
<pre> | |||
SKIN LESION, LEFT NIPPLE AREOLA, EXCISION: | |||
- DERMAL SCAR WITH KELOIDAL-TYPE COLLAGEN, CONSISTENT WITH HYPERTROPHIC SCAR. | |||
</pre> | |||
==See also== | |||
*[[Non-malignant skin disease]]. | |||
==References== | |||
{{Reflist|1} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Dermatopathology]] | |||