Difference between revisions of "Diverticular disease"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Diverticulum_-_very_low_mag.jpg | |||
| Width = | |||
| Caption = Diverticulum. [[H&E stain]]. | |||
| Micro = mucosa/submucosa invaginate into the musuclaris propria | |||
| Subtypes = | |||
| LMDDx = | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[colon]], other sites | |||
| Assdx = peritonitis | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = usu. asymptomatic, diverticulitis presents with abdominal pain | |||
| Prevalence = | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = [[colorectal carcinoma]] (occasionally) | |||
}} | |||
'''Diverticular disease''', also '''diverticulosis''', is a common disease of the [[colon]]. Inflammation of diverticula is known as '''diverticulitis'''. | |||
===General=== | |||
*Very common. | |||
Complications: | |||
*Diverticulitis. | |||
*Diverticular-associated colitis<ref name=pmid19581849>{{Cite journal | last1 = Mulhall | first1 = AM. | last2 = Mahid | first2 = SS. | last3 = Petras | first3 = RE. | last4 = Galandiuk | first4 = S. | title = Diverticular disease associated with inflammatory bowel disease-like colitis: a systematic review. | journal = Dis Colon Rectum | volume = 52 | issue = 6 | pages = 1072-9 | month = Jun | year = 2009 | doi = 10.1007/DCR.0b013e31819ef79a | PMID = 19581849 }}</ref> - rare. | |||
**Rectal biopsy to differentiate from [[ulcerative colitis]]. | |||
===Gross=== | |||
*Corrugated - like cardboard. | |||
*Wall thickening (reactive).<ref name=pmid21359889>{{Cite journal | last1 = Nicholson | first1 = BD. | last2 = Hyland | first2 = R. | last3 = Rembacken | first3 = BJ. | last4 = Denyer | first4 = M. | last5 = Hull | first5 = MA. | last6 = Tolan | first6 = DJ. | title = Colonoscopy for colonic wall thickening at computed tomography: a worthwhile pursuit? | journal = Surg Endosc | volume = 25 | issue = 8 | pages = 2586-91 | month = Aug | year = 2011 | doi = 10.1007/s00464-011-1591-7 | PMID = 21359889 }}</ref> | |||
====Endoscopic image==== | |||
<gallery>Image:Diverticulosis_2.jpg | Diverticular disease. (WC/Samir)</gallery> | |||
====Grossing notes==== | |||
*[[pp:Diverticular disease]]. | |||
===Microscopic=== | |||
Features: | |||
*Mucosa/submucosa invagination into the musuclaris propria (MP). | |||
**At the site the blood vessels supplying the mucosa and submucosa penetrate the MP.<ref name=pmid18936652>{{Cite journal | last1 = West | first1 = AB. | title = The pathology of diverticulitis. | journal = J Clin Gastroenterol | volume = 42 | issue = 10 | pages = 1137-8 | month = | year = | doi = 10.1097/MCG.0b013e3181862a9f | PMID = 18936652 }}</ref> | |||
Image: | |||
*[http://histology-group28.wikispaces.com/file/view/divertic.jpg/60992930/divertic.jpg DD (wikispaces.com)].<ref>URL: [http://histology-group28.wikispaces.com/DigestiveSystemProject http://histology-group28.wikispaces.com/DigestiveSystemProject]. Accessed on: 23 August 2011.</ref> | |||
===Sign out=== | |||
<pre> | |||
RECTO-SIGMOID, LARGE BOWEL RESECTION: | |||
- PERFORATED DIVERTICULITIS WITH SEROSITIS AND ABSCESS FORMATION. | |||
- SUBMUCOSAL FIBROSIS. | |||
- ONE LYMPH NODE NEGATIVE FOR MALIGNANCY ( 0 POSITIVE / 1 ). | |||
- NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
<pre> | |||
SIGMOID COLON, SIGMOIDECTOMY: | |||
- DIVERTICULAR DISEASE WITHOUT DIVERTICULITIS. | |||
- NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
==See also== | |||
*[[Colon]]. | |||
*[[Gastrointestinal pathology]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
Revision as of 22:00, 4 August 2013
| Diverticular disease | |
|---|---|
| Diagnosis in short | |
 Diverticulum. H&E stain. | |
|
| |
| LM | mucosa/submucosa invaginate into the musuclaris propria |
| Site | colon, other sites |
|
| |
| Associated Dx | peritonitis |
| Symptoms | usu. asymptomatic, diverticulitis presents with abdominal pain |
| Clin. DDx | colorectal carcinoma (occasionally) |
Diverticular disease, also diverticulosis, is a common disease of the colon. Inflammation of diverticula is known as diverticulitis.
General
- Very common.
Complications:
- Diverticulitis.
- Diverticular-associated colitis[1] - rare.
- Rectal biopsy to differentiate from ulcerative colitis.
Gross
- Corrugated - like cardboard.
- Wall thickening (reactive).[2]
Endoscopic image
Diverticular disease. (WC/Samir)
Grossing notes
Microscopic
Features:
- Mucosa/submucosa invagination into the musuclaris propria (MP).
- At the site the blood vessels supplying the mucosa and submucosa penetrate the MP.[3]
Image:
Sign out
RECTO-SIGMOID, LARGE BOWEL RESECTION: - PERFORATED DIVERTICULITIS WITH SEROSITIS AND ABSCESS FORMATION. - SUBMUCOSAL FIBROSIS. - ONE LYMPH NODE NEGATIVE FOR MALIGNANCY ( 0 POSITIVE / 1 ). - NEGATIVE FOR MALIGNANCY.
SIGMOID COLON, SIGMOIDECTOMY: - DIVERTICULAR DISEASE WITHOUT DIVERTICULITIS. - NEGATIVE FOR MALIGNANCY.
See also
References
- ↑ Mulhall, AM.; Mahid, SS.; Petras, RE.; Galandiuk, S. (Jun 2009). "Diverticular disease associated with inflammatory bowel disease-like colitis: a systematic review.". Dis Colon Rectum 52 (6): 1072-9. doi:10.1007/DCR.0b013e31819ef79a. PMID 19581849.
- ↑ Nicholson, BD.; Hyland, R.; Rembacken, BJ.; Denyer, M.; Hull, MA.; Tolan, DJ. (Aug 2011). "Colonoscopy for colonic wall thickening at computed tomography: a worthwhile pursuit?". Surg Endosc 25 (8): 2586-91. doi:10.1007/s00464-011-1591-7. PMID 21359889.
- ↑ West, AB.. "The pathology of diverticulitis.". J Clin Gastroenterol 42 (10): 1137-8. doi:10.1097/MCG.0b013e3181862a9f. PMID 18936652.
- ↑ URL: http://histology-group28.wikispaces.com/DigestiveSystemProject. Accessed on: 23 August 2011.