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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Traditional_serrated_adenoma_very_high_mag.jpg | |||
| Width = Traditional serrated adenoma. [[H&E stain]]. | |||
| Caption = | |||
| Micro = serrated, eosinophilic cytoplasm, villous-like architecture | |||
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| LMDDx = [[villous adenoma]] | |||
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| Site = [[colon]] - usu. left side / [[gastrointestinal polyps]] | |||
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}} | |||
'''Traditional_serrated_adenoma''', abbreviated '''TSA''', are a rare type of [[gastrointestinal polyp]]. | |||
==General== | |||
*Very rare. | |||
==Gross== | |||
*Usually left colon. | |||
==Microscopic== | |||
Features:<ref name=pmid17516746>{{cite journal |author=Li SC, Burgart L |title=Histopathology of serrated adenoma, its variants, and differentiation from conventional adenomatous and hyperplastic polyps |journal=Arch. Pathol. Lab. Med. |volume=131 |issue=3 |pages=440-5 |year=2007 |month=March |pmid=17516746 |doi= |url=http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=131&page=440}}</ref> | |||
*Serrated - '''essential'''. | |||
*Eosinophilic cytoplasm - '''key feature'''. | |||
*Nuclear atypia as in [[tubular adenoma]]. | |||
**Nuclear hyperchromasia, enlargement and pseudostratification. | |||
*Villous-like architecture. | |||
DDx: | |||
*[[Villous adenoma]]. | |||
===Images=== | |||
<gallery> | |||
Image:Traditional_serrated_adenoma_low_mag.jpg | TSA - low mag. (WC/Nephron) | |||
Image:Traditional_serrated_adenoma_intermed_mag.jpg | TSA - intermed. mag. (WC/Nephron) | |||
Image:Traditional_serrated_adenoma_very_high_mag.jpg | TSA - very high mag. (WC/Nephron) | |||
</gallery> | |||
==See also== | |||
*[[Gastrointestinal polyps]]. | |||
*[[Gastrointestinal pathology]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Gastrointestinal pathology]] |
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