Difference between revisions of "Traditional serrated adenoma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Traditional_serrated_adenoma_very_high_mag.jpg | |||
| Width = Traditional serrated adenoma. [[H&E stain]]. | |||
| Caption = | |||
| Micro = serrated, eosinophilic cytoplasm, villous-like architecture | |||
| Subtypes = | |||
| LMDDx = [[villous adenoma]] | |||
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| Grossing = | |||
| Site = [[colon]] - usu. left side / [[gastrointestinal polyps]] | |||
| Assdx = | |||
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}} | |||
'''Traditional_serrated_adenoma''', abbreviated '''TSA''', are a rare type of [[gastrointestinal polyp]]. | |||
==General== | |||
*Very rare. | |||
==Gross== | |||
*Usually left colon. | |||
==Microscopic== | |||
Features:<ref name=pmid17516746>{{cite journal |author=Li SC, Burgart L |title=Histopathology of serrated adenoma, its variants, and differentiation from conventional adenomatous and hyperplastic polyps |journal=Arch. Pathol. Lab. Med. |volume=131 |issue=3 |pages=440-5 |year=2007 |month=March |pmid=17516746 |doi= |url=http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=131&page=440}}</ref> | |||
*Serrated - '''essential'''. | |||
*Eosinophilic cytoplasm - '''key feature'''. | |||
*Nuclear atypia as in [[tubular adenoma]]. | |||
**Nuclear hyperchromasia, enlargement and pseudostratification. | |||
*Villous-like architecture. | |||
DDx: | |||
*[[Villous adenoma]]. | |||
===Images=== | |||
<gallery> | |||
Image:Traditional_serrated_adenoma_low_mag.jpg | TSA - low mag. (WC/Nephron) | |||
Image:Traditional_serrated_adenoma_intermed_mag.jpg | TSA - intermed. mag. (WC/Nephron) | |||
Image:Traditional_serrated_adenoma_very_high_mag.jpg | TSA - very high mag. (WC/Nephron) | |||
</gallery> | |||
==See also== | |||
*[[Gastrointestinal polyps]]. | |||
*[[Gastrointestinal pathology]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Gastrointestinal pathology]] | |||
Revision as of 19:26, 9 July 2013
| Traditional serrated adenoma | |
|---|---|
| Diagnosis in short | |
 | |
|
| |
| LM | serrated, eosinophilic cytoplasm, villous-like architecture |
| LM DDx | villous adenoma |
| Site | colon - usu. left side / gastrointestinal polyps |
|
| |
Traditional_serrated_adenoma, abbreviated TSA, are a rare type of gastrointestinal polyp.
General
- Very rare.
Gross
- Usually left colon.
Microscopic
Features:[1]
- Serrated - essential.
- Eosinophilic cytoplasm - key feature.
- Nuclear atypia as in tubular adenoma.
- Nuclear hyperchromasia, enlargement and pseudostratification.
- Villous-like architecture.
DDx:
Images
TSA - low mag. (WC/Nephron)
TSA - intermed. mag. (WC/Nephron)
TSA - very high mag. (WC/Nephron)
See also
References
- ↑ Li SC, Burgart L (March 2007). "Histopathology of serrated adenoma, its variants, and differentiation from conventional adenomatous and hyperplastic polyps". Arch. Pathol. Lab. Med. 131 (3): 440-5. PMID 17516746. http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=131&page=440.