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Difference between revisions of "Traditional adenoma"
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| Width = | | Width = | ||
| Caption = Tubular adenoma. [[H&E stain]]. | | Caption = Tubular adenoma. [[H&E stain]]. | ||
| Micro = | | Micro = nuclear changes - esp. at the surface (hyperchromatic elongated nuclei or round cleared nuclei), nuclear crowding/pseudostratification, +/- loss of nuclear polarity, loss/decrease of goblet cells, cytoplasmic hyperchromasia | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[tubular adenoma]], [[villous adenoma]], [[tubulovillous adenoma]], [[sessile serrated adenoma]] with dysplasia | | LMDDx = [[tubular adenoma]], [[villous adenoma]], [[tubulovillous adenoma]], [[sessile serrated adenoma]] with dysplasia | ||
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| Assdx = [[colorectal adenocarcinoma]] | | Assdx = [[colorectal adenocarcinoma]] | ||
| Syndromes = [[Familial adenomatous polyposis]] | | Syndromes = [[Familial adenomatous polyposis]] | ||
| Signs = rectal bleeding | | Signs = usually asymptomatic, may present with rectal bleeding | ||
| Symptoms = | | Symptoms = uncommon, usually asymptomatic | ||
| Prevalence = common | | Prevalence = common | ||
| Bloodwork = anemia | | Bloodwork = +/-anemia | ||
| Rads = polyp | | Rads = polyp | ||
| Endoscopy = polyp - pedunculated or sessile | | Endoscopy = polyp - pedunculated or sessile | ||
| Prognosis = | | Prognosis = good | ||
| Other = | | Other = | ||
| ClinDDx = invasive [[colorectal adenocarcinoma]], benign colorectal mucosa, [[hyperplastic polyp]] | | ClinDDx = invasive [[colorectal adenocarcinoma]], benign colorectal mucosa, [[hyperplastic polyp]] | ||