Difference between revisions of "Desmoplasia"
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*[[Sclerosing adenosis]]. | *[[Sclerosing adenosis]]. | ||
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Image:Cecal_adenocarcinoma.jpg | Desmoplasia in a cecal adenocarcinoma. (WC/Nephron) | |||
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*[http://missinglink.ucsf.edu/lm/IDS_107_Cervix_Ovary_Uterus/ASSETS/Slide329SCChp.JPG Desmoplasia in cervical SCC (ucsf.edu)].<ref name=uscf>URL: [http://missinglink.ucsf.edu/lm/IDS_107_Cervix_Ovary_Uterus/homepage.htm http://missinglink.ucsf.edu/lm/IDS_107_Cervix_Ovary_Uterus/homepage.htm]. Accessed on: 2 May 2013.</ref> | *[http://missinglink.ucsf.edu/lm/IDS_107_Cervix_Ovary_Uterus/ASSETS/Slide329SCChp.JPG Desmoplasia in cervical SCC (ucsf.edu)].<ref name=uscf>URL: [http://missinglink.ucsf.edu/lm/IDS_107_Cervix_Ovary_Uterus/homepage.htm http://missinglink.ucsf.edu/lm/IDS_107_Cervix_Ovary_Uterus/homepage.htm]. Accessed on: 2 May 2013.</ref> | ||
Revision as of 01:47, 19 May 2013
Desmoplasia is the formation if fibrous connective tissue.[1] It is also known as the desmoplastic response, desmoplastic stroma, and desmoplastic stromal response.
It is a stromal change that in the context of dysplasia supports the diagnosis of an invasive carcinoma.
Microscopic
Feature:
- Increased stromal cellularity - key feature.
- Large (plump) spindle cells (fibroblasts) with relatively pale, large nuclei.
- Edema - pale spaces between the cells - may be apparent at low power.[2]
DDx:
Images
Desmoplasia in a cecal adenocarcinoma. (WC/Nephron)
www:
See also
References
- ↑ URL: http://www.merriam-webster.com/medical/desmoplasia. Accessed on: 2 May 2013.
- ↑ Weedman Molavi, Diana (2008). The Practice of Surgical Pathology: A Beginner's Guide to the Diagnostic Process (1st ed.). Springer. pp. 15. ISBN 978-0387744858.
- ↑ URL: http://missinglink.ucsf.edu/lm/IDS_107_Cervix_Ovary_Uterus/homepage.htm. Accessed on: 2 May 2013.