Difference between revisions of "Sjögren syndrome"

Sjögren syndrome (view source)

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 ==Microscopic==
 Features ([[salivary gland]]):<ref name=pmid19323360/>
-*Viable [[salivary gland]] (or [[lacrimal gland]]) acini with significant lymphocytic infiltration - '''key feature'''.
+*Viable [[salivary gland]] (or [[lacrimal gland]]) acini adjacent to a significant lymphocytic infiltrate - '''key feature'''.
-**Plasma cells should not exceed 10% of the inflammatory infiltrate.<ref name=pmid12022353/>
+**"Significant" lymphocytic infiltrate: cluster of >= 50 lymphocytes - '''important'''.
-**"Significant" infiltrate = cluster of >= 50 lymphocytes - '''important'''.
 ***Lymphocytes that are perivascular count.<ref name=pmid12022353/>
-***May have "benign lymphoepithelial lesion"<ref name=pmid15956090/> - intraepithelial lymphocytes.
+***[[Plasma cell]]s should not exceed 10% of the inflammatory infiltrate.<ref name=pmid12022353/>
+***May have "benign lymphoepithelial lesions"<ref name=pmid15956090/> - intraepithelial lymphocytes.
 *+/-Fibrosis.