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*Onset in males earlier than females (due to menses). | *Onset in males earlier than females (due to menses). | ||
*Mutation thought to confer survival advantage - several theories (increased resistance to TB, S. typhi vs. decr. iron def./incr. iron absorption)<ref name=pmid18192769/> | *Mutation thought to confer survival advantage - several theories (increased resistance to TB, S. typhi vs. decr. iron def./incr. iron absorption)<ref name=pmid18192769/> | ||
*May lead to [[cardiomyopathy#Restrictive cardiomyopathy|restrictive cardiomyopathy]]. | |||
===Pathophysiology=== | ===Pathophysiology=== |
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