Difference between revisions of "Testis"

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315 bytes added ,  02:26, 2 February 2013
→‎Seminoma: more images
(→‎Seminoma: more images)
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*Rarely, it may present a retroperitoneal mass.<ref name=pmid21424055>{{Cite journal  | last1 = Preda | first1 = O. | last2 = Nicolae | first2 = A. | last3 = Loghin | first3 = A. | last4 = Borda | first4 = A. | last5 = Nogales | first5 = FF. | title = Retroperitoneal seminoma as a first manifestation of a partially regressed (burnt-out) testicular germ cell tumor. | journal = Rom J Morphol Embryol | volume = 52 | issue = 1 | pages = 193-6 | month =  | year = 2011 | doi =  | PMID = 21424055 }}</ref>
*Rarely, it may present a retroperitoneal mass.<ref name=pmid21424055>{{Cite journal  | last1 = Preda | first1 = O. | last2 = Nicolae | first2 = A. | last3 = Loghin | first3 = A. | last4 = Borda | first4 = A. | last5 = Nogales | first5 = FF. | title = Retroperitoneal seminoma as a first manifestation of a partially regressed (burnt-out) testicular germ cell tumor. | journal = Rom J Morphol Embryol | volume = 52 | issue = 1 | pages = 193-6 | month =  | year = 2011 | doi =  | PMID = 21424055 }}</ref>


===Epidemiology & etiology===
====Epidemiology & etiology====
*Arises from ''intratubular germ cell neoplasia'' (ITGCN).
*Arises from ''[[intratubular germ cell neoplasia]]'' (ITGCN).


===Microsopic===
===Microsopic===
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Memory device: 3 Cs - clear cytoplasm, central nucleus, corners on the nuclear membrane.
Memory device: 3 Cs - clear cytoplasm, central nucleus, corners on the nuclear membrane.
Images:
*[http://commons.wikimedia.org/wiki/File:Seminoma_high_mag.jpg Seminoma - high mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Seminoma_intermed_mag.jpg Seminoma - intermed. mag. (WC)].


DDx:
DDx:
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*[[Choriocarcinoma]] - esp. if (multinucleated) syncytiotrophoblasts are present.<ref name=pmid157614>{{Cite journal  | last1 = Hedinger | first1 = C. | last2 = von Hochstetter | first2 = AR. | last3 = Egloff | first3 = B. | title = Seminoma with syncytiotrophoblastic giant cells. A special form of seminoma. | journal = Virchows Arch A Pathol Anat Histol | volume = 383 | issue = 1 | pages = 59-67 | month = Jul | year = 1979 | doi =  | PMID = 157614 }}</ref>
*[[Choriocarcinoma]] - esp. if (multinucleated) syncytiotrophoblasts are present.<ref name=pmid157614>{{Cite journal  | last1 = Hedinger | first1 = C. | last2 = von Hochstetter | first2 = AR. | last3 = Egloff | first3 = B. | title = Seminoma with syncytiotrophoblastic giant cells. A special form of seminoma. | journal = Virchows Arch A Pathol Anat Histol | volume = 383 | issue = 1 | pages = 59-67 | month = Jul | year = 1979 | doi =  | PMID = 157614 }}</ref>
*Granulomatous orchitis - if [[granuloma]]s are present.
*Granulomatous orchitis - if [[granuloma]]s are present.
Images:
*[http://commons.wikimedia.org/wiki/File:Seminoma_high_mag.jpg Seminoma - high mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Seminoma_intermed_mag.jpg Seminoma - intermed. mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Seminoma_with_syncytiotrophoblasts_-_intermed_mag.jpg Seminoma with syncytiotrophoblasts - intermed. mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Seminoma_with_syncytiotrophoblasts_-_very_high_mag.jpg Seminoma with syncytiotrophoblasts - very high mag. (WC)].


===IHC===
===IHC===
48,790

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