48,830
edits
Difference between revisions of "Granular cell tumour"
Jump to navigation
Jump to search
m
w
(tweak lead) |
m (w) |
||
| Line 4: | Line 4: | ||
*Rare. | *Rare. | ||
*Usually benign. | *Usually benign. | ||
*May seen in the context of ''LEOPARD syndrome'' and a mutation in the ''PTPN11 gene''.<ref name=pmid19054014>{{Cite journal | last1 = Schrader | first1 = KA. | last2 = Nelson | first2 = TN. | last3 = De Luca | first3 = A. | last4 = Huntsman | first4 = DG. | last5 = McGillivray | first5 = BC. | title = Multiple granular cell tumors are an associated feature of LEOPARD syndrome caused by mutation in PTPN11. | journal = Clin Genet | volume = 75 | issue = 2 | pages = 185-9 | month = Feb | year = 2009 | doi = 10.1111/j.1399-0004.2008.01100.x | PMID = 19054014 }}</ref> | *May seen in the context of ''[[LEOPARD syndrome]]'' and a mutation in the ''PTPN11 gene''.<ref name=pmid19054014>{{Cite journal | last1 = Schrader | first1 = KA. | last2 = Nelson | first2 = TN. | last3 = De Luca | first3 = A. | last4 = Huntsman | first4 = DG. | last5 = McGillivray | first5 = BC. | title = Multiple granular cell tumors are an associated feature of LEOPARD syndrome caused by mutation in PTPN11. | journal = Clin Genet | volume = 75 | issue = 2 | pages = 185-9 | month = Feb | year = 2009 | doi = 10.1111/j.1399-0004.2008.01100.x | PMID = 19054014 }}</ref> | ||
**PTPN11 = protein-tyrosine phosphatase non-receptor type 11.<ref>{{OMIM|176876}}</ref> | **PTPN11 = protein-tyrosine phosphatase non-receptor type 11.<ref>{{OMIM|176876}}</ref> | ||
***Gene implicated in ''[[Noonan syndrome]] 1''. | ***Gene implicated in ''[[Noonan syndrome]] 1''. | ||