Difference between revisions of "Hypertension"
Jump to navigation
Jump to search
(→Kidney: +stuff) |
m (→Kidney) |
||
| Line 24: | Line 24: | ||
==Kidney== | ==Kidney== | ||
* | ===General=== | ||
*May result in renal failure. | |||
===Microscopic=== | |||
Features:<ref name=pmid9356598>{{cite journal |author=Ono H, Ono Y |title=Nephrosclerosis and hypertension |journal=Med. Clin. North Am. |volume=81 |issue=6 |pages=1273–88 |year=1997 |month=November |pmid=9356598 |doi= |url=}}</ref> | Features:<ref name=pmid9356598>{{cite journal |author=Ono H, Ono Y |title=Nephrosclerosis and hypertension |journal=Med. Clin. North Am. |volume=81 |issue=6 |pages=1273–88 |year=1997 |month=November |pmid=9356598 |doi= |url=}}</ref> | ||
*Fibrinoid necrosis of afferent and interlobular arteries (due to endothelial cell damage). | |||
==See also== | ==See also== | ||
Revision as of 21:41, 23 September 2010
Hypertension is very common and affects multiple organs. Clinically, it is usually classified as primary (idiopathic) and secondary.
Brain
Charcôt-Bouchard aneurysms
General
- AKA miliary aneurysms.
- Intracerebral hemorrhages.
Microscopic
Features:[1]
- Small aneurysms (~300 micrometers) with a fusiform shape.
- Vessel wall changes:
- Early:
- Proliferation of arteriolar smooth muscle
- Late:
- Apoptotic smooth muscle cell death and collagen deposition.
- Early:
Image: C-B aneurysm (ucsf.edu).
Eye
- Blindness.
Heart
- Concentric hypertrophy.
Kidney
General
- May result in renal failure.
Microscopic
Features:[2]
- Fibrinoid necrosis of afferent and interlobular arteries (due to endothelial cell damage).