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Difference between revisions of "Vulva"
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→Microscopic
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**May appear pale - directly deep to the epidermis.<ref>URL: [http://www.webpathology.com/image.asp?n=2&Case=538 http://www.webpathology.com/image.asp?n=2&Case=538]. Accessed on: 25 August 2011.</ref> | **May appear pale - directly deep to the epidermis.<ref>URL: [http://www.webpathology.com/image.asp?n=2&Case=538 http://www.webpathology.com/image.asp?n=2&Case=538]. Accessed on: 25 August 2011.</ref> | ||
*Inflammation - often with eosinophils. | *Inflammation - often with eosinophils. | ||
**May be prominent - in the ''inflammatory phase'' of the disease.<ref name=pmid9537476>{{Cite journal | last1 = Fung | first1 = MA. | last2 = LeBoit | first2 = PE. | title = Light microscopic criteria for the diagnosis of early vulvar lichen sclerosus: a comparison with lichen planus. | journal = Am J Surg Pathol | volume = 22 | issue = 4 | pages = 473-8 | month = Apr | year = 1998 | doi = | PMID = 9537476 }}</ref> | |||
DDx: | DDx: | ||
*[[Morphea profunda]] - deep fibrosis. | *[[Morphea profunda]] - deep fibrosis. | ||
*[[Differentiated vulvar intraepithelial neoplasia]] - commonly co-exists with lichen sclerosus. | *[[Differentiated vulvar intraepithelial neoplasia]] - commonly co-exists with lichen sclerosus. | ||
*[[Lichen planus]] - has | *[[Lichen planus]] (LP) - esp. for the ''inflammatory phase of lichen sclerosus''. | ||
**LP has wedge shaped hypergranulosis, lacks basilar epidermotropism, no epidermal atrophy.<ref name=pmid9537476/> | |||
Images: | Images: | ||