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Difference between revisions of "Prostate cancer"
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→Prostatic ductal adenocarcinoma: more tweaking
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(→Prostatic ductal adenocarcinoma: more tweaking) |
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_GUP88>{{Ref GUP|88}}</ref> | Features:<ref name=Ref_GUP88>{{Ref GUP|88}}</ref> | ||
#Pseudostratified (crowded appearing) columnar (or cigar-shaped) nuclei - '''key feature'''. | |||
#*Vaguely resembles [[colonic adenocarcinoma]]. | |||
#Compatible architecture: | |||
#*Papillary. | |||
#*Cribriform. | |||
#*Single gland (large glands). | |||
#*Endometrioid - vaguely looks like [[endometrioid endometrial carcinoma]] (with back-to-back glands). | |||
#>= 50% of tumour.<ref name=pmid21383610/> | |||
#*If ductal component <50%, it is a conventional (acinar) adenocarcinoma with a ductal component. | |||
Notes: | Notes: | ||
*Proportion of ductal component should be quantified: | |||
**<10% ductal component of no prognostic significance.<ref name=pmid21383610>{{Cite journal | last1 = Amin | first1 = A. | last2 = Epstein | first2 = JI. | title = Pathologic stage of prostatic ductal adenocarcinoma at radical prostatectomy: effect of percentage of the ductal component and associated grade of acinar adenocarcinoma. | journal = Am J Surg Pathol | volume = 35 | issue = 4 | pages = 615-9 | month = Apr | year = 2011 | doi = 10.1097/PAS.0b013e31820eb25b | PMID = 21383610 }}</ref> | |||
Images: | Images: | ||