Difference between revisions of "Osteoarthritis"

From Libre Pathology
Jump to navigation Jump to search
(+micro)
Line 18: Line 18:
Memory device ''LOSS'': ''L''oss of cartilage, ''O''steophyte formation, ''S''ubchondral cysts, ''S''ubchondral sclerosis.
Memory device ''LOSS'': ''L''oss of cartilage, ''O''steophyte formation, ''S''ubchondral cysts, ''S''ubchondral sclerosis.


==Microscopic==
Features:<ref name=Ref_WMSP658>{{Ref WMSP|658}}</ref>
*Vertical clefts of the cartilage - characteristic.
*Thickening of [[bone|bony]] trabeculae (reactive phenomenon) due to fibrosis.
*Subchondral cysts.
*+/-Mild inflammation (lymphocytes).
==See also==
==See also==
*[[Soft tissue lesions]].
*[[Soft tissue lesions]].
Line 25: Line 32:


==References==
==References==
{{Reflist|1}}
{{Reflist|2}}


[[Category:Soft tissue lesions]]
[[Category:Soft tissue lesions]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]

Revision as of 12:27, 9 October 2012

Osteoarthritis, abbreviated OA, is a degenerative disease of the joint.

General

Risks

It is associated with:[1]

  • Advanced age.
  • Trauma.
  • Unusual loading (bony misalignment, obesity).

Gross pathology/radiology

Features:[2]

  • Loss of cartilage, especially asymmetrical (eburnation).
  • Osteophyte formation.
  • Subchondral cysts.
  • Subchondral sclerosis.

Memory device LOSS: Loss of cartilage, Osteophyte formation, Subchondral cysts, Subchondral sclerosis.

Microscopic

Features:[3]

  • Vertical clefts of the cartilage - characteristic.
  • Thickening of bony trabeculae (reactive phenomenon) due to fibrosis.
  • Subchondral cysts.
  • +/-Mild inflammation (lymphocytes).

See also

References

  1. Martel-Pelletier, J.; Pelletier, JP. (Apr 2010). "Is osteoarthritis a disease involving only cartilage or other articular tissues?". Eklem Hastalik Cerrahisi 21 (1): 2-14. PMID 20302555. http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.tevak.org-images-Eklemlinkout.png.
  2. Swagerty, DL.; Hellinger, D. (Jul 2001). "Radiographic assessment of osteoarthritis.". Am Fam Physician 64 (2): 279-86. PMID 11476273. http://www.aafp.org/afp/2001/0715/p279.html.
  3. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 658. ISBN 978-0781765275.