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Difference between revisions of "Melanocytic lesions"
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Melanocytic lesions (view source)
Revision as of 21:19, 18 September 2012
, 21:19, 18 September 2012→Dysplastic melanocytic nevus
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Treatment: | Treatment: | ||
* | *Dysplastic nevi with severe nuclear atypia are treated like melanoma - excision with a 5 mm margin. | ||
*Moderate nuclear atypia with margin involvement are re-excised.<ref name=pmid15509670>{{Cite journal | last1 = Culpepper | first1 = KS. | last2 = Granter | first2 = SR. | last3 = McKee | first3 = PH. | title = My approach to atypical melanocytic lesions. | journal = J Clin Pathol | volume = 57 | issue = 11 | pages = 1121-31 | month = Nov | year = 2004 | doi = 10.1136/jcp.2003.008516 | PMID = 15509670 }}</ref> | |||
===Gross=== | ===Gross=== | ||
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Features:<ref name=Ref_WMSP502>{{Ref WMSP|502}}</ref> | Features:<ref name=Ref_WMSP502>{{Ref WMSP|502}}</ref> | ||
*Melanocytes "bridges" between sides of rete ridges. | *Melanocytes "bridges" between sides of rete ridges. | ||
**Joining of three or more adjacent rete ridges = suspicious for melanoma.<ref name=pmid15509670/> | |||
*Drapping fibrous tissue - "lamellar fibrosis" - collagen deep to epidermis. | *Drapping fibrous tissue - "lamellar fibrosis" - collagen deep to epidermis. | ||
*Usually moderate nuclear atypia (small nucleoli present) - see ''grading'' section. | *Usually moderate nuclear atypia (small nucleoli present) - see ''grading'' section. | ||