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*S-100 +ve. | *S-100 +ve. | ||
*Ki-67 -- only rare cells. | *Ki-67 -- only rare cells. | ||
==Solar lentigo== | |||
===General=== | |||
*Benign. | |||
Fits into the larger category of ''lentiginous melanocytic proliferations'' - these include:<ref name=Ref_Derm438>{{Ref Derm|438}}</ref> | |||
*Solar lentigo. | |||
*Lentigo simplex. | |||
*Lentiginous nevus. | |||
*Lentiginous melanoma in situ. | |||
===Gross=== | |||
Features:<ref name=Ref_Derm438>{{Ref Derm|438}}</ref> | |||
*Small (< 4 mm), irregular brown macule. | |||
*Usu. sun-exposed area. | |||
===Microscopic=== | |||
Features:<ref name=Ref_Derm437>{{Ref Derm|437}}</ref> | |||
*Hyperpigmented melanocytes - may be present in increased quantities - '''key feature'''. | |||
**Classically at the tips of the rete ridges. | |||
*No (melanocyte) nuclear atypia. | |||
Notes: | |||
*Should ''not'' be present:<ref name=Ref_Derm438>{{Ref Derm|438}}</ref> | |||
**Nests of melanocytes. | |||
**Pagetoid spread of melanocytes. | |||
==See also== | ==See also== |
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